Hoat Huyet Nhat Nhat Versus Tanakan for Treatment of Symptoms Related to the Insufficient Blood Supply to the Brain

Completed

• Conditions: Insufficient Blood Supply to the Brain
• Interventions: Drug: Hoat Huyet Nhat Nhat; Drug: Tanakan 40mg

• Registration Number: NCT03216681
• Lead Sponsor: Nhat Nhat Pharmaceutical Company

Brief Summary

The purpose of this study is to evaluate the effectiveness of Hoat Huyet Nhat Nhat on the reduction of common symptoms related to the insufficient blood supply to the brain such as headache, vertigo, dizziness, sleep disorders and forgetfulness; compared with Gingko Biloba Egb761 (Tanakan) after 45 days of treatment

Detailed Description

Not available

Study Timeline

• Status Verified: 2017-07
• Study Start: 2017-07-01
• Study First Submitted: 2017-07-09
• Study First Submitted QC: 2017-07-11
• Study First Posted: 2017-07-13
• Primary Completion: 2018-04-01
• Study Completion: 2018-04-30
• Last Update Submitted: 2018-10-20
• Last Update Posted: 2018-10-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 750

Inclusion Criteria

• Male and Female more than 18 year old.
• With at least one of the symptoms related to the insufficient blood supply to the brain scored more than 5 out 10, on the Visual Analog Scale.
• Patients who will be using either Hoat Huyet Nhat Nhat or Tanakan following doctor's prescription or by patients own decision.
• Sign the informed consent form

Exclusion Criteria

• Use of any medications for treatment of the insufficient blood supply to the brain in the last 3 months

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Hoat Huyet Nhat Nhat	Hoat Huyet Nhat Nhat	Administered orally twice a day, 2 tablets each time, for 45 days.
Tanakan 40mg	Tanakan 40mg	Administered orally three times a day, one tablet each time, for 45 days.

Primary Outcome Measures

Name	Time	Method
The percentage of patients with symptoms related to the insufficient blood supply to the brain recovered after 45 days of treatment as assessed by Symptom Improvement Likert Scale in Hoat Huyet Nhat Nhat and Tanakan 40mg group	45 days

Secondary Outcome Measures

Name	Time	Method
Change From Baseline to 45 days of the severity of vertigo symptom in patients with symptoms related to the insufficient blood supply to the brain as assessed by Visual Analog Scale (VAS)	45 days
Change From Baseline to 45 days of the severity of dizziness symptom in patients with symptoms related to the insufficient blood supply to the brain as assessed by Visual Analog Scale (VAS)	45 days
Change From Baseline to 45 days of the severity of sleep disorders symptom in patients with symptoms related to the insufficient blood supply to the brain as assessed by Visual Analog Scale (VAS)	45 days
Change From Baseline to 45 days of the severity of forgetfulness symptom in patients with symptoms related to the insufficient blood supply to the brain as assessed by Visual Analog Scale (VAS)	45 days
Change From Baseline to 45 days of the severity of all symptoms related to the insufficient blood supply to the brain as assessed by Khadjev Score	45 days
Change From Baseline to 45 days of the severity of headache symptom in patients with symptoms related to the insufficient blood supply to the brain as assessed by Visual Analog Scale (VAS)	45 days
The number of participants with clinically significant vital sign parameters at Day 45.	45 days
The number of participants with clinically significant laboratory parameters at Day 45.	45 days

Trial Locations

Locations (1)

Vietnam Military Medical University; 🇻🇳 Hanoi, Vietnam