STUDY THE EFFECT OF MUSCLE RELAXANT ON FACEMASK VENTILATION

Not yet recruiting

Conditions: Medical and Surgical,

Registration Number: CTRI/2023/01/049352

Lead Sponsor: MS RAMAIH MEDICAL COLLEGE

Brief Summary: Facemask ventilation is the most fundamental and important skill for safe airway management during induction of anaesthesia. Upper airway obstruction encountered during ventilation may occur at the oropharynx, soft palate or epiglottis which can be overcome with the triple airway manoeuvre - head tilt, chin lift and jaw thrust ( advancing the mandible forward so the lower teeth are in front of the upper teeth). Even in difficult tracheal intubation, facemask ventilation is an alternative step to ensure sufficient oxygenation until the patientâ€™s airway is secured. Some of the studies conclude that the neuromuscular blocking agent facilitates tracheal intubation and might improve facemask ventilation. and other studies says neuromuscular blockade neither improve nor hindered mask ventilation in patient with normal airway. Difficult mask ventilation secondary to laryngospasm and opioid-induced muscle rigidity can be improved following administration of neuromuscular blocking agent, making mask ventilation easier. Even a minute increase in tidal volume is potentially clinically significant in hypoxic patient. Study of this topic has an important implication for the question of whether neuromuscular blockade should be administered following adequate mask ventilation or not. Therefore, the main aim of study is to assess the impact of neuromuscular block on facemask ventilation in term of tidal volume. The primary outcome is the tidal volume measuring before and after neuromuscular blockade. Secondary outcome will be comparing audible mask leakage and gastric insufflation before and after neuromuscular blockade.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 110

Inclusion Criteria

PATIENT SCHEDULED TO UNDERGO ELECTIVE SURGERY.

Exclusion Criteria

PATIENT REFUSAL ANTICIPATED DIFFICULT AIRWAY OBESE PATIENT INCREASED RISK OF PULMONARY ASPIRATION ( GASTRO-OESOPHAGEAL REFLUX , FULL STOMACH AND INTESTINAL OBSTRUCTION) ALLERGIC TO STUDY DRUG PREGNANCY NEUROMUSCULAR DISORDERS HEPATIC AND RENAL INSUFFICIENCY PATIENT REQUIRING ORAL AIRWAY FOR EFFECTIVE MECHANICAL VENTILATION.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
MEASURING TIDAL VOLUME (12 BREATHS)BEFORE AND AFTER ADMINISTRATION OF NEUROMUSCULAR BLOCKING AGENT DURING FACEMASK VENTILATION	BEFORE GIVING MUSCLE RELAXANT AND THREE MINUTES AFTER GIVING MUSCLE RELAXANT

Secondary Outcome Measures

Name	Time	Method
COMPARING AUDIBLE MASK LEAKAGE AND GASTRIC INSUFFLATION BEFORE AND AFTER NEUROMUSCULAR BLOCKADE	BEFORE NEUROMUSCULAR BLOCKADE AND AFTER NEUROMUSCULAR BLOCKADE

Trial Locations

Locations (1): MS RAMAIAH MEDICAL COLLEGE HOSPITAL
🇮🇳
Bangalore, KARNATAKA, India
MS RAMAIAH MEDICAL COLLEGE HOSPITAL
🇮🇳Bangalore, KARNATAKA, India
DR LEENA H PARATE
Principal investigator
09480525925
dr_leenag@yahoo.co.in