Comparing of Computed Tomography Guided Microcoil Localization and Hook Wire Localization for Pulmonary Small Nodules and Ground-glass Opacity Prior to Thoracoscopic Resection
Trial Snapshot
- Phase
- Phase 3
- Enrollment
- 72
- Locations
- 1
- Primary Endpoint
- complications after CT-guided localization
Study Overview
Brief Summary
Both of microcoil localization and hookwire localization have been proved as good preoperative CT(computed tomography)-guided techniques to guide VATS resection for the diagnosis of small peripheral pulmonary nodules technique to guide VATS resection for the diagnosis of small peripheral pulmonary nodules. The objective of this study is to determine if microcoil localization for pulmonary nodules can be safer than hookwire localization
Detailed Description
Both of microcoil localization and hookwire localization have been proved as good preoperative CT-guided techniques to guide VATS resection for the diagnosis of small peripheral pulmonary nodules technique to guide VATS(video assisted thoracoscopic surgery) resection for the diagnosis of small peripheral pulmonary nodules. Compared with the commonly used hook wire, the platinum microcoil can be retained in the patients'body and the configuration of which had an effect in reducing the severity of complications. The fibered microcoil may promote blood coagulation of the surrounding lung tissues, block the needle pathway, and decrease the severity of pneumothorax and bleeding caused by the puncture needle, which has been proven in animal experiments. The objective of this study is to determine if microcoil localization for pulmonary nodules can be safer than hookwire localization
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •solid nodules with a diameter ≤1 cm and distance to visceral pleura ≥0.5 cm, -ground-glass nodules,
- •part-solid ground-glass nodules, with a solid portion ≤1 cm and distance to the visceral pleura ≥1 cm.
- •peripheral nodules amenable to thoracoscopic wedge excision of the nodules.
Exclusion Criteria
- •Patients combined with pneumothorax.
- •Patients combined with pleural effusion.
- •Patients with history of hemoptysis.
- •Patients with medical condition that the radiologist and surgeon disagree for inclusion.
Outcomes
Primary Outcomes
complications after CT-guided localization
Time Frame: 1 years
any complication occured after CT-guided localization
Secondary Outcomes
- major complications after CT-guided localization(1 years)
- success of the localization by thoracoscopic surgery(1 year)
- success of the intervention of localization(1 year)
Investigators
Jun Wang
Pro
Peking University People's Hospital