Comparing of Computed Tomography Guided Microcoil Localization and Hook Wire Localization for Pulmonary Small Nodules and Ground-glass Opacity Prior to Thoracoscopic Resection
试验速览
- 阶段
- 3 期
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- complications after CT-guided localization
研究概览
简要总结
Both of microcoil localization and hookwire localization have been proved as good preoperative CT(computed tomography)-guided techniques to guide VATS resection for the diagnosis of small peripheral pulmonary nodules technique to guide VATS resection for the diagnosis of small peripheral pulmonary nodules. The objective of this study is to determine if microcoil localization for pulmonary nodules can be safer than hookwire localization
详细描述
Both of microcoil localization and hookwire localization have been proved as good preoperative CT-guided techniques to guide VATS resection for the diagnosis of small peripheral pulmonary nodules technique to guide VATS(video assisted thoracoscopic surgery) resection for the diagnosis of small peripheral pulmonary nodules. Compared with the commonly used hook wire, the platinum microcoil can be retained in the patients'body and the configuration of which had an effect in reducing the severity of complications. The fibered microcoil may promote blood coagulation of the surrounding lung tissues, block the needle pathway, and decrease the severity of pneumothorax and bleeding caused by the puncture needle, which has been proven in animal experiments. The objective of this study is to determine if microcoil localization for pulmonary nodules can be safer than hookwire localization
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •solid nodules with a diameter ≤1 cm and distance to visceral pleura ≥0.5 cm, -ground-glass nodules,
- •part-solid ground-glass nodules, with a solid portion ≤1 cm and distance to the visceral pleura ≥1 cm.
- •peripheral nodules amenable to thoracoscopic wedge excision of the nodules.
排除标准
- •Patients combined with pneumothorax.
- •Patients combined with pleural effusion.
- •Patients with history of hemoptysis.
- •Patients with medical condition that the radiologist and surgeon disagree for inclusion.
研究组 & 干预措施
microcoil
patients who plan for microcoil localization
干预措施: microcoil localization (Procedure)
hookwire
patients who plan for hookwire localization
干预措施: hookwire localization (Procedure)
结局指标
主要结局
complications after CT-guided localization
时间窗: 1 years
any complication occured after CT-guided localization
次要结局
- major complications after CT-guided localization(1 years)
- success of the localization by thoracoscopic surgery(1 year)
- success of the intervention of localization(1 year)
研究者
Jun Wang
Pro
Peking University People's Hospital