Vitamin D Production Depends on Ultraviolet-B Dose But Not on UV-intensity. A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 55
- 试验地点
- 1
- 主要终点
- Vitamin D (nmol/l)
研究概览
简要总结
The purpose of the study is to determine the importance of the UV intensity and the UVB dose on the Vitamin D response after UVB.
详细描述
The work is addressing vitamin D production after UVB exposure and explore the importance of UVB dose and UV intensity. Four different UVB doses and four different UV intensities are used to explore these relationships.
Many assumptions have been made concerning the vitamin D production after UVB exposure but only few studies exist.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •18-65 years
排除标准
- •Sun bed use
- •Holiday or business travel south of 45 degrees latitude during trial
- •Drug addiction
- •Pregnancy
- •Lactating
研究组 & 干预措施
Group 4
UV intensity 20 MIN
干预措施: UVB (Radiation)
Group 3
UV intensity 1 MIN
干预措施: UVB (Radiation)
Group 1
UV intensity 10 MIN
干预措施: UVB (Radiation)
Group 2
UV intensity 5 MIN
干预措施: UVB (Radiation)
结局指标
主要结局
Vitamin D (nmol/l)
时间窗: 2 days after exposure
Vitamin D measured in a blood sample to define the dose-response relationship between UVB dose, UV intensity and Vitamin D production in the skin after UVB exposure.
次要结局
- Other parameters(2 days after radiation)