Injection of Combination of 5-Fluorouracil and Triamcinolone versus Triamcinolone alone in Keloids
Not Applicable
- Conditions
- Health Condition 1: L918- Other hypertrophic disorders of the skin
- Registration Number
- CTRI/2021/06/034079
- Lead Sponsor
- ok Nayak Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All patients between 18-60 years, having keloid scars with maximum scar size of 20 cm2.
-If one patient has multiple scars, no more than two scar sites will be included in the study.
Exclusion Criteria
-Pregnancy and lactation
-Patients with co-morbidities like uncontrolled diabetes, hypertension, cardio-pulmonary disease, chronic liver / kidney disease with deranged LFT/KFT.
-Any patient with history of treatment with intralesional TAC and /or 5-FU injection in previous 6 months for the same site.
-Infected keloids
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical scar assessment by Vancouver Scar Scale (VSS) parameters of scar height, pliability, vascularity & pigmentation.Timepoint: Before 1st session (pre-drug), at every session and till last follow up at monthly intervals for subsequent 2 months after the last session.
- Secondary Outcome Measures
Name Time Method Pain, Pruritis, Telangiectasia, Ulceration, Infection, Atrophy, Pigmentary changes, POSAS score, any other.Timepoint: Before 1st session (pre-drug), at every session and till last follow up at monthly intervals for subsequent 2 months after the last session.