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Exploring the potential of pupil-dilating and pupil-constricting eye drops as a treatment for presbyopia

Phase 4
Completed
Conditions
Presbyopia
Eye - Diseases / disorders of the eye
Registration Number
ACTRN12623000297628
Lead Sponsor
The University of Auckland
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
19
Inclusion Criteria

Healthy adults who are willing and able to provide written informed consent for study participation.

Exclusion Criteria

- Significant refractive error, defined as over 6 Dioptres of myopic or hyperopic mean sphere refractive error
- History of ocular pathology or intraocular surgery that has the potential to affect the participant’s vision at the time of study participation
- A personal or family history of epilepsy or seizures, neurological disorders/ disease, or serious head injury and/or skull fracture, as these may affect performance in MRI procedures involving viewing flickering visual patterns (e.g. epilepsy) and/or lying still for an extended period of time (e.g. claustrophobia)
- Having metal implants (e.g. a cardiac pacemaker) or other contraindications that would put the safety of the participant at risk when undergoing an MRI scan
- Pregnant or breastfeeding women, as safety of the eye drops used in this study has not been established for use in pregnancy and lactation. For this reason, participants who become pregnant during the study will also not be able to continue participation.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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