COMPARISON OF ULTRASOUND GUIDED ERECTOR SPINAE PLANE BLOCK (PAIN RELIEF TECHNIQUE) PERFORMED WITH DIFFERENT CONCENTRATIONS OF MEDICINE (BUPIVACAINE) FOR POST SURGERY PAIN SEVERITY, SURGICAL STRESS AND SATISFACTION IN PATIENTS UNDERGOING GALL BLADDER REMOVAL (LAPAROSCOPIC CHOLECYSTECTOMY) SURGERY.
- Conditions
- Health Condition 1: K802- Calculus of gallbladder without cholecystitis
- Registration Number
- CTRI/2021/07/034629
- Lead Sponsor
- Dr Ali Saloda
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 90
All patients aged 18-65yrs, posted for elective laparoscopic cholecystectomy, with American society of Anaesthesiologist (ASA) physical status I-II shall be included in the study.
1. Patient refusal.
2. Patients with known allergy to local anaesthetics.
3. Patients with presence of bleeding disorders.
4. Patients with infection at injection sites.
5. Patients with prior addiction or analgesics abuse (opioid and nonsteroidal anti-inflammatory drug medications).
6. Patients with BMI <18.5kg/m2 and >34.9kg/m2.
7. Patients with weight under 50kgs.
8. Patients with liver or renal insufficiency.
9. Patients with history of psychiatric or neurological disease, deafness.
10. Patients in whom the total surgical duration exceeds 2 hours (after incision) or surgery is converted to open cholecystectomy.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the reduction in Numerical Rating Scale (NRS) score at 30 minutes after extubation between the control group, group receiving ESPB with bupivacaine 0.25% and the group receiving ESPB with bupivacaine 0.375% respectively.Timepoint: 30 minutes after extubation
- Secondary Outcome Measures
Name Time Method 1. To compare total intraoperative fentanyl requirement in the 3 groups. <br/ ><br>2. To compare total analgesic consumption postoperatively in 24 hours between the 3 groups. <br/ ><br>3. To compare change in pre and post-operative surgical stress markers (NLR- neutrophil-lymphocyte ratio, PLR- platelet-lymphocyte ratio, Serum albumin, Blood glucose) between the 3 groups. <br/ ><br>4. To compare patient satisfaction scores between the three groups. <br/ ><br>Timepoint: 24 hours after extubation. <br/ ><br>For stress markers- 6 hours and 24 hours after extubation