A clinical study to see the effect of some Ayurvedic formulation in the treatment of far sightedness.

Phase 2

Completed

• Conditions: Hypermetropia. Ayurveda Condition: TIMIRAH,

• Registration Number: CTRI/2021/12/038889
• Lead Sponsor: Sane Guruji Arogya Kendra

Brief Summary

1. The progress of the disease Timira has mentioned in terms of involvement of successive Patalas (layers of eyeball). When the vitiated Doshas invades first Patala, the patient complains of difficulty in distance vision and if not treated it shifts to next patala. 2. Visual disturbance is represented as one of the most complex problem in the field of ophthalmology and it has a great interest ever since the dawn of human life[5]. 3. Hypermetropia is that form of refractive error in which parallel rays of light are bought to a focus some distance behind the sentient layer of the retina when the eye is at rest, the image formed here is therefore made up of circles of diffusion of considerable size, and is consequently blurred [6]. 4. Small amount of hypermetropia in young patients up to +0.50 D for distant is usually corrected by their accommodation, without any defects in vision .If the hypermetropia is high i.e., above +1D there will be defective vision for both distance and near. 5. People may also experience accommodative dysfunction, binocular dysfunction, strabismus and amblyopia. In modern science use of spectacles, contact lenses, laser in situ, keratomiesis, refractive keratometry is been advised. But these all have some limitations. These doesn’t prevent the pathology of refractive error so the blurring of vision continues .Surgeries are costly for everyone and at the same time this operations have some complications.

Bhaskar Ghrita Nasya is an easy and affordable procedure, and also it prevents pathology of Timir, whereas Saptamrita Lauha is best drug to prevent the pathology of Timir. Dravyas included in Bhaskar Ghrita yoga are Yastimadhu, Draksha, Mishri (Khanda),Pippali. Acharya Vangsena has described Bhaskar Ghrita which is selected for study .Dravyas included in Saptamrita Lauha are Yastimadhu, Amalaki, Bibtaki, Haritiki and Lauha Bhasma. In Bhaishajya Ratnavali Saptamrita Lauha has been described in chapter 64 Netra Roga. Purpose of study is to find out solution for Prathama and Dwitiya Patalgata Timir.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-01-03
• Study Completion: 2023-12-21
• Last Update Posted: 2024-08-03

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 56

Inclusion Criteria

• Patients having symptoms of Prathama Dwitiya Patalgata Timir will be included.
• Patients who have ≤ +5 D in both the eyes 3.
• The patient age from 18 years to 60 years of age 4.
• Patient having vision of 6/9 or less i.e., 6/12, 6/18,6/24, 6/36, 6/60.
• Patient yogya for Nasya Karma.
• Patient of either gender will be included in the study.

Exclusion Criteria

• Patients having symptoms of Tritiya and Chaturtha Patalgata Timir will be excluded like Kacha and Linganasha.
• Patient suffering from infectious disease e.g.-viral, bacterial or fungal conjunctivitis, blepharitis and trachoma.
• Patient having known case of Hypertension, HIV, TB, Rheumatic Heart Disease, Bronchial Asthma, Thyroid disorder.
• Hypermetropia associated with other ocular disease such as cataract, glaucoma, retinal disease, chorioretinitis, iridocyclitis, choroidal disease, vitreal opacity, cornel opacity, corneal ulcer.
• Congenital, Acquired non physiological hypermetropia like index hyermetropia, pseudophakic hypermetropia.
• Refractive errors like astigmatism, myopia, presbyopia and other ocular pathologies will be excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
A clinical study to evaluate efficacy of Bhaskar Ghrita Nasya and Saptamrita Lauha Vati in Prathama and Dwitiya Patalgata Timir w.r.t Hypermetropia. Parameter of efficacy will be visual acuity before and after treatment	Follow up will betaken on 1st, 11th and 21st day. Parameter of efficacy will be visual acuity before and after treatment

Secondary Outcome Measures

Name	Time	Method
A comparison between efficacy of Bhaskar Ghrita Nasya with Saptamrita Lauha and Saptamrita Lauha alone in Prathama and Dwitiya Patalgata Timir w.r.t Hypermetropia	Total duration of the study will 18 months.

Trial Locations

Locations (1)

Sane Guruji Arogya Kendra,Malwadi road, Hadapsar, Pune-411028; 🇮🇳 Pune, MAHARASHTRA, India

Sane Guruji Arogya Kendra,Malwadi road, Hadapsar, Pune-411028

🇮🇳Pune, MAHARASHTRA, India

Vd Sayali Sahas Patil

Principal investigator

08097480795

sayalipatil661@gmail.com