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Clinical Trials/NCT05760911
NCT05760911
Not yet recruiting
Not Applicable

A Multi-center Clinical Study on the Myopia Prevention by Monitoring and Motivating Outdoor Activities With Smartwatches

Shanghai Eye Disease Prevention and Treatment Center0 sites1,200 target enrollmentMarch 15, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Myopia, Progressive
Sponsor
Shanghai Eye Disease Prevention and Treatment Center
Enrollment
1200
Primary Endpoint
The change of spherical equivalent
Status
Not yet recruiting
Last Updated
3 years ago

Overview

Brief Summary

The goal of this multi-center, randomized, parallel-controlled clinical trial is to evaluate the effectiveness of outdoor activities monitoring and motivating by smartwatches to prevent myopia progression in children. The main question it aims to answer are:

  1. To evaluate the two-year change of spherical equivalent progression.
  2. To evaluate the change in axial length, the incidence of myopia, the time of outdoor activity, the choroid thickness, and blood flow through the two-year intervention.

Participants will wear smartwatches and receive Mini Program outdoor activity reminders and motivations. The required outdoor activity time is 2 hours from Monday to Friday and more than 2 hours on weekends. The control group will only wear smartwatches for monitoring. Researchers will compare the control group and the intervention group to see if outdoor activities can protect myopia or not.

Registry
clinicaltrials.gov
Start Date
March 15, 2023
End Date
September 30, 2024
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Gender is not limited;
  • Age: 4 \~ 9 years old;
  • Spherical equivalent: -0.5D \< SE \< 2.5D;
  • Be able to follow up for at least 2 years;
  • Be able to wear a smartwatch on a daily basis as required;
  • Parents or guardians sign an informed consent form;
  • Children over 6 years old need oral consent to participate.

Exclusion Criteria

  • Anisometropia \> 1.50D;
  • Using other interventions for controlling myopia including atropine, rigid orthokeratology lenses, bifocal lenses or progressive lenses, red light, acupuncture, etc.;
  • Strabismus and/or amblyopia;
  • Previous history of eye surgery (including strabismus correction);
  • Ocular or systemic diseases that may be related to the development of myopia or myopia: such as Marfan syndrome, neonatal retinopathy, diabetes, etc.;
  • Other circumstances that the investigator judges inappropriate to participate in the trial.

Outcomes

Primary Outcomes

The change of spherical equivalent

Time Frame: Two years

The mean change of spherical equivalent after cycloplegia was calculated during the study.

Secondary Outcomes

  • The change of axial length(Two years)

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