Tofacitinib and azathioprine in alopecia areata
Phase 3
Recruiting
- Conditions
- Alopecia Areata.Alopecia areata
- Registration Number
- IRCT20220904055876N1
- Lead Sponsor
- ady Reading Hospital Peshawar Pakistan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Patients having Alopecia areata with =50% scalp hair loss, Alopecia totalis and Alopecia universalis.
Patients must not have received any treatments for Alopecia areata within 2 months of enrollment and will not permitted to use any other treatment known to affect AA
Stable or worsening disease for =6 months
Exclusion Criteria
Active malignancy or a history of malignancy
Leukopenia, Anemia
Hepatic or renal impairment
Human immunodeficiency virus, Hepatitis B and C.
Pregnant or nursing women
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of Alopecia Tool (SALT) score. Treatment will be considered efficacious if percent change in SALT score is > 50%. Timepoint: before intervention and 3 months and 6 months after intervention. Method of measurement: Severity of Alopecia Tool (SALT) score.
- Secondary Outcome Measures
Name Time Method