Randomized controlled trial of a comparison between ritonavir-boosted atazanavir with tenofovir plus emtricitabine versus rilpivirine with tenofovir plus emtricitabine in occupational post-exposure prophylaxis for HIV infectio

Phase 4

Recruiting

• Conditions: Occupational post- exposure prophylaxis for HIV infection; Comparison; Rilpivirine; Ritonavir- boosted atazanavir; exposure prophylaxis; Randomized controlled trial

• Registration Number: TCTR20190311001
• Lead Sponsor: King Chulalongkorn Memorial Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2019-02-19
• Study Start: 2019-03-11
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 82

Inclusion Criteria

>18-year-old of age
occupational exposure to HIV less than 72 hours

Exclusion Criteria

non-occupational exposure to HIV
allergic to study drugs
HIV-negative source

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Completion rate 28 days after initiation of intervention Chi-square test

Secondary Outcome Measures

Name	Time	Method
Adherence 28 days after initiation of intervention Chi square test,Side effects 28 days after initiation of intervention Chi square test,Change of total bilirubin level 28 days after initiation of intervention student t-test,Seroconversion 28 days & 90 days after initiation of intervention Chi square test