Quadratus lumborum block versus Transversus abdominis plane block for postoperative analgesia in children undergoing abdominal surgeries: a prospective randomized controlled trial
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Cumulative opioid consumption in terms of iv morphine equivalents in 24 hours after surgery.
研究概览
简要总结
Major abdominal surgeries in children is optimally managed with multimodal analgesia, with the goal of reducing opioid use and associated side effects. Regional anesthesia techniques are useful adjuncts of multimodal analgesia for decreasing postoperative pain and opioid consumption. Development of new and accessible nerve blocks and improved ultrasound technology has increased the focus of non-neuraxial regional anesthesia techniques in children. Transversus abdominis plane (TAP) block and Quadratus lumborum (QL) block provides intraoperative and postoperative analgesia for upper and lower abdominal incisions. Data demonstrating feasibility and safety of these techniques are increasing, but procedure specific evidence for major abdominal surgeries in children is lacking. Thus, our study aims at comparing analgesic efficacy of TAP block and QL block in children undergoing abdominal surgeries.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 5.00 Year(s) 至 15.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA grade I & II.
排除标准
- •Failure to obtain parental consent
- •Emergency surgeries
- •ASA grade III,IV,V
- •Children who will be electively ventilated postoperatively
- •Past history of allergic reaction to local anesthetic agent.
结局指标
主要结局
Cumulative opioid consumption in terms of iv morphine equivalents in 24 hours after surgery.
时间窗: Within 24 hours after surgery
次要结局
- Pain scores(1hr)
- Time to first rescue analgesia(Within 24 hours of surgery)
- Number of rescue analgesia(Within 24 hours after surgery)
- Postoperative vomiting and retching(Within 24 hours after surgery)
- Parent satisfaction score using Likert scale(Within 24 hours after surgery)
- Procedure related complications(Within 24 hours after surgery)
研究者
Dr ANULAKSHMI T V
All India Institute of Medical Sciences Bhubaneswar