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临床试验/NCT05678049
NCT05678049尚未招募不适用

Evaluation and Characterisation of Microplastics and Nanoplastics in Joint Synovial Liquid

Universitatea de Medicina si Farmacie Iuliu Hatieganu0 个研究点目标入组 50 人开始时间: 2023年1月15日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
50
主要终点
nanoplastics

研究概览

简要总结

The research study aims to evaluate the synovial fluid to highlight the presence of possible micropolymers (micro/nanoplastics) in order to better understand the pathophysiology of joint degenerative processes. For patients with liquid under tension at the joint level, the symptomatology often requires evacuation by puncture under ultrasound guidance. The intervention will be performed only for patients for whom this therapeutic indication exists anyway by their physician.

The investigators want to use this liquid for Microscopic and Spectrophotometric evaluation.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • arthritis of the knee with liquid aspiration recommendation
  • age >18 years

排除标准

  • -refusal of the patient to participate
  • age<18 years

结局指标

主要结局

nanoplastics

时间窗: immediately after liquid extraction

evaluation with spectrophotometry and optic microscopy

microplastics

时间窗: immediately after liquid extraction

evaluation with spectrophotometry and optic microscopy

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ciubean Alina Deniza

Director

Universitatea de Medicina si Farmacie Iuliu Hatieganu

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