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Clinical Trials/NCT05678049
NCT05678049
Not yet recruiting
Not Applicable

Evaluation and Characterisation of Microplastics and Nanoplastics in Joint Synovial Liquid

Universitatea de Medicina si Farmacie Iuliu Hatieganu0 sites50 target enrollmentJanuary 15, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Osteoarthritis, Knee
Sponsor
Universitatea de Medicina si Farmacie Iuliu Hatieganu
Enrollment
50
Primary Endpoint
nanoplastics
Status
Not yet recruiting
Last Updated
3 years ago

Overview

Brief Summary

The research study aims to evaluate the synovial fluid to highlight the presence of possible micropolymers (micro/nanoplastics) in order to better understand the pathophysiology of joint degenerative processes. For patients with liquid under tension at the joint level, the symptomatology often requires evacuation by puncture under ultrasound guidance. The intervention will be performed only for patients for whom this therapeutic indication exists anyway by their physician.

The investigators want to use this liquid for Microscopic and Spectrophotometric evaluation.

Registry
clinicaltrials.gov
Start Date
January 15, 2023
End Date
December 15, 2024
Last Updated
3 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Ciubean Alina Deniza

Director

Universitatea de Medicina si Farmacie Iuliu Hatieganu

Eligibility Criteria

Inclusion Criteria

  • arthritis of the knee with liquid aspiration recommendation
  • age \>18 years

Exclusion Criteria

  • -refusal of the patient to participate
  • age\<18 years

Outcomes

Primary Outcomes

nanoplastics

Time Frame: immediately after liquid extraction

evaluation with spectrophotometry and optic microscopy

microplastics

Time Frame: immediately after liquid extraction

evaluation with spectrophotometry and optic microscopy

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