The impact of low level laser treatment on skeletal muscle and skin tissue mitochondrial respiration, metabolic activity and signaling in vivo in humans
- Conditions
- Muscle and skin research (no disorders)muscleskin
- Registration Number
- NL-OMON56671
- Lead Sponsor
- niversiteit Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 16
Inclusion Criteria
• Male or female sex
• Aged between 18 and 35 y inclusive
• BMI between 18.5 and 30 kg/m2
Exclusion Criteria
• Participating in a structured (progressive) exercise program or >4h of
vigorous physical activity per week.
• Smoking regularly (i.e. >5 cigarettes/week)
• Pregnancy
• Hormonal replacement therapy
• Diagnosed musculoskeletal disorders
• Diagnosed metabolic disorders (e.g. diabetes)
• Diagnosed skin disorders
• Use of any medications known to affect protein metabolism (i.e.
corticosteroids, non-steroidal anti-inflammatories).
• Chronic use of anti-coagulants
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The primary outcome will be mitochondrial respiration of the LLLT treated and<br /><br>non-treated leg based on muscle samples. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Secondary study parameters are muscle and skin gene expression, protein<br /><br>signalling and enzyme activity. </p><br>