跳至主要内容
临床试验/NCT04813458
NCT04813458Unknown不适用

A Multi-centre Survey on Tramadol Abuse in Singapore

Singapore General Hospital3 个研究点 分布在 1 个国家目标入组 1,000 人开始时间: 2020年12月1日最近更新:
适应症

试验速览

阶段
不适用
入组人数
1,000
试验地点
3
主要终点
Current Opioid Misuse Measure (COMM)

研究概览

简要总结

The rampant prescription of opioid has in part contributed to the ongoing worldwide opioid crisis. In the United States of America, it is estimated that death from the use of opioids outnumber death from motor vehicle accident deaths by more than 40%. Consequently, many countries such as America and Canada have drawn up guidelines pertaining to safe opioid prescribing.

Tramadol is often used by pain physicians to treat chronic pain. As it is a weak opioid and unscheduled in many countries, it is often considered to have a lower addiction potential compared to strong opioids. Despite this, the literature does reveal evidence of abuse, addiction and withdrawal - although the incidence of this is unclear.

In this study, the investigators aim to determine the prevalence of tramadol misuse in a pain clinic population. The investigators also aim to determine the real-life compliance of physicians to guidelines provided by International regulatory bodies (CDC) and the modifiable risk factors associated with tramadol misuse.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

性别
All
接受健康志愿者

入选标准

  • All patients attending pain clinic in Singapore General Hospital, Seng Kang General Hospital and Changi General Hospital

排除标准

  • 未提供

结局指标

主要结局

Current Opioid Misuse Measure (COMM)

时间窗: Baseline

The primary outcome is the prevalence of Current Opioid Misuse (defined as a COMM score of 9 or greater) in the patients included in the cross-sectional study (ie patients who are on tramadol)

次要结局

  • Opioid Risk Tool (ORT)(Baseline)
  • Patient Health Questionnaire-9 (PHQ-9)(Baseline)
  • General Anxiety Disorder-7 (GAD-7)(Baseline)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (3)

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