NCT05283603招募中不适用
Registro Osservazionale Dei Pazienti Con Blocco Della Branca Sinistra
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- Left ventricular dysfunction
研究概览
简要总结
The electromechanical dyssynchrony induced by the presence of LBBB is in some patients, but not all, the cause of progressive left ventricular systolic dysfunction and heart failure.
Aims
- To investigate the clinical, ECG, imaging-derived features in a large cohort of patients affected by LBBB on ECG.
- To identify predictors of LBBB-induced LV systolic dysfunction and predictors of outcome in this population.
- To derive data which may have an impact on therapeutic management.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •LBBB on ECG
排除标准
- •Previous extensive anterior myocardial infarction
- •Previous cardiac surgery or transcatheter aortic valve implantation (TAVI)
- •Congenital structural heart disease
- •Patients implanted with permanent right ventricular stimulation devices and permanent pacing
- •Denial to consent
结局指标
主要结局
Left ventricular dysfunction
时间窗: 20 years
Echocardiographic left ventricular ejection fraction - EF (%)
次要结局
- Adverse cardiovascular events (e.g., heart failure)(20 years)
研究者
Giuseppe Damiano Sanna
MD PhD
Azienda Ospedaliero Universitaria di Sassari
研究点 (1)
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