Role of Asthisharinkhala Ghana Guggulu in the management of Osteoarthritis

Phase 2/3

Completed

• Conditions: Osteoarthritis of knee, unspecified, patient with osteoarthritis,

• Registration Number: CTRI/2018/05/014093
• Lead Sponsor: OPD and IPD department of panchakarma

Brief Summary

Osteoarthritis (OA), which is also known as osteoarthrosis or degenerative joint disease (DJD), is a progressive disorderof the joints caused by gradual loss of cartilage and resulting in the development of bony spurs and cysts at the margins of the joints.The condition similar to Osteoarthritis has been described as *‘Sandhigatavata’* in *Ayurveda*, in which the vitiated *Vata* afflicts the joints and causes destruction of the cartilages and reduction in the synovial Fluid inside the joint capsule, leading to swelling which results into painful movement. Ayurvedic treatment of Osteoarthritis prevents further deterioration in the joints and rejuvenates damaged cartilages. Vata-alleviating treatments through specific herbs are suggested for lubrication and strengthening of joints.

Detailed Description

Not available

Study Timeline

• Study Completion: 2017-06-05
• Study Start: 2018-03-26
• Last Update Posted: 2019-12-31

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Having sign and symptoms of Sandhivata (Osteoarthritis) as given below: 1.
• Sandhi Shula (pain in the joint) 2.
• Sandhi Shotha (Swelling in the joints) 3.
• Sandhigraha (Morning Stiffness) 4.
• Akunchana Prasaranayoh Vedana (Pain during Flexion and extension) 5.
• Sparsha Asahyata (Tenderness) 6.
• Sandhisphutana (Cracking of the joints) 7.
• Crepitus in the joint.
• Diagnostic Findings: 1.
• Radiologic Osteophytes (If present) c.
• Chronicity less than or equal to 5 years.

Exclusion Criteria

• Patients below 30 and above 70 years of age.
• Cases which require surgical intervention will be excluded.
• Patient, suffering from any chronic debilitating disease like T.B., D.M., Rheumatoid Arthritis, Gout, Varicose veins, Asthma & other chronic problems etc.
• and having other serious pathology.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Complete relief : 100%	2 year
given scoring depending upon there severity.	2 year
2. Marked improvement : 76% to 99	2 year
4. Mild improvement : 26 % to 50 %	2 year
5. No improvement : 0% to 25 %	2 year
To assess the effect of therapy all sign and symptoms were	2 year
3. Moderate improvement : 51% to 75 %	2 year

Secondary Outcome Measures

Name	Time	Method
Exacerbation in signs and synptoms	30 DAYS

Trial Locations

Locations (1)

Rishikul Campus, Haridwar; 🇮🇳 Hardwar, UTTARANCHAL, India

Rishikul Campus, Haridwar

🇮🇳Hardwar, UTTARANCHAL, India

Kshiteeja Choudhary

Principal investigator

9001214122

choudharykshiteeja@gmail.com