Epidemiology and Long Term Outcome of Critically Ill Patients Requiring Renal Replacement Therapy in Southeast Asia and India (InSEA-RRT Registry)

Recruiting

• Conditions: Acute Kidney Injury

• Registration Number: NCT03727997
• Lead Sponsor: Chulalongkorn University

Brief Summary

Acute kidney injury is associated with increased short-term and long-term morbidity and mortality. Long-term data is lacking in low to middle-income countries. Our study aims to follow the acute kidney injury patients stage 3 in intensive care units for 2 years to observe mortality and associated factors.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-10-26
• Study First Submitted QC: 2018-10-31
• Study First Posted: 2018-11-01
• Study Start: 2019-04-01
• Primary Completion: 2022-12-01
• Status Verified: 2024-02
• Last Update Submitted: 2024-02-05
• Last Update Posted: 2024-02-07
• Study Completion: 2024-12-01

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 5000

Inclusion Criteria

• AKI stage 3
• At least 18 years old

Exclusion Criteria

• ESRD patients (eGFR < 15 mL/min/1.73 m2)

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
2-year mortality	2-year

Secondary Outcome Measures

Name	Time	Method
Hospital mortality	28-day
Renal recovery	28-day	Number of Participants with who survive. Number of Participants with dialysis independence and creatinine \<1.5 mg/dL
RRT rate	28-day
2-year major adverse kidney events	2-year	Number of Participants with 25% or greater decline in eGFR. Number of participants who receive new renal replacement therapy (RRT).

Trial Locations

Locations (1)

Faculty of Medicine, Chulalongkorn University; 🇹🇭 Bangkok, Pathumwan, Thailand