NCT05001035CompletedNot Applicable
Effect of Different Biomimetic Materials on White Spot Lesions in Enamel
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Benha University
- Enrollment
- 21
- Locations
- 1
- Primary Endpoint
- change in remineralization from base line to time limit
Study Overview
Brief Summary
This study will be conducted to evaluate: 1- The remineralizing effect of different biomimetic materials (Zinc carbonate hydroxyapatite nanoparticles, Poly-amido amine (PAMAM) and bioactive glass nanoparticles) on white spot lesions in enamel. 2- The clinical efficacy of these agents on disappearance of these white spots.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Treatment
- Masking
- Triple (Participant, Investigator, Outcomes Assessor)
Eligibility Criteria
- Ages
- 15 Years to 25 Years (Child, Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Total of 21 patients enrolled in this study will be selected having at least 4 teeth (one on each quadrant) which will be extracted for orthodontic treatment.
- •These patients will be selected according to age groups between 15-25 years old
- •good oral hygiene
- •free of destroying habits for dental tissues
Exclusion Criteria
- •soft drinks consumption
- •acid regurgitation, etc.).
- •Selected teeth having any cracks, malformations, dysplasia or caries.
Outcomes
Primary Outcomes
change in remineralization from base line to time limit
Time Frame: Immediate and one month and two months
Change in its density in digital xray
changes of appearance from base line photograph to time limit
Time Frame: Immediate and one month and two months
White spots disappear on digital photography
Secondary Outcomes
No secondary outcomes reported
Investigators
Eptesam Atef
Dental specialist at benha teaching hospital
Benha University
Study Sites (1)
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