Effect of Different Biomimetic Materials on White Spot Lesions in Enamel
Not Applicable
Completed
- Conditions
- White Spot Lesion
- Registration Number
- NCT05001035
- Lead Sponsor
- Benha University
- Brief Summary
This study will be conducted to evaluate: 1- The remineralizing effect of different biomimetic materials (Zinc carbonate hydroxyapatite nanoparticles, Poly-amido amine (PAMAM) and bioactive glass nanoparticles) on white spot lesions in enamel. 2- The clinical efficacy of these agents on disappearance of these white spots.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 21
Inclusion Criteria
- Total of 21 patients enrolled in this study will be selected having at least 4 teeth (one on each quadrant) which will be extracted for orthodontic treatment.
- These patients will be selected according to age groups between 15-25 years old
- good oral hygiene
- free of destroying habits for dental tissues
Exclusion Criteria
- Bruxism
- soft drinks consumption
- acid regurgitation, etc.).
- Selected teeth having any cracks, malformations, dysplasia or caries.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method change in remineralization from base line to time limit Immediate and one month and two months Change in its density in digital xray
changes of appearance from base line photograph to time limit Immediate and one month and two months White spots disappear on digital photography
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Faculty of dental medicine for girls branch of Alazhar University
🇪🇬Cairo, Egypt
Faculty of dental medicine for girls branch of Alazhar University🇪🇬Cairo, Egypt