Effect of Different Biomimetic Materials on White Spot Lesions in Enamel
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 21
- 试验地点
- 1
- 主要终点
- changes of appearance from base line photograph to time limit
研究概览
简要总结
This study will be conducted to evaluate: 1- The remineralizing effect of different biomimetic materials (Zinc carbonate hydroxyapatite nanoparticles, Poly-amido amine (PAMAM) and bioactive glass nanoparticles) on white spot lesions in enamel. 2- The clinical efficacy of these agents on disappearance of these white spots.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 15 Years 至 25 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Total of 21 patients enrolled in this study will be selected having at least 4 teeth (one on each quadrant) which will be extracted for orthodontic treatment.
- •These patients will be selected according to age groups between 15-25 years old
- •good oral hygiene
- •free of destroying habits for dental tissues
排除标准
- •soft drinks consumption
- •acid regurgitation, etc.).
- •Selected teeth having any cracks, malformations, dysplasia or caries.
研究组 & 干预措施
Zinc carbonated hydroxy apatite
Toothpaste to be added on white spot lesions in dental enamel
干预措施: Time of assessment (Other)
Bioactive glass
Toothpaste to be added on white spot lesions in dental enamel
干预措施: Time of assessment (Other)
Poly amido amine
Resinous material to be painted on white spot lesions in dental enamel
干预措施: Time of assessment (Other)
Control
No material to be added
结局指标
主要结局
changes of appearance from base line photograph to time limit
时间窗: Immediate and one month and two months
White spots disappear on digital photography
change in remineralization from base line to time limit
时间窗: Immediate and one month and two months
Change in its density in digital xray
次要结局
未报告次要终点
研究者
Eptesam Atef
Dental specialist at benha teaching hospital
Benha University