Clinical, microbiological, radiographical and heamatological evaluation of implant surface decontamination using air polishing in the non- surgical treatment of peri-implantitis; a randomized controlled study

Phase 4

Completed

• Conditions: peri-implant disease; peri-implant infection; 10004018

• Registration Number: NL-OMON43349
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2019-11-20
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 80

Inclusion Criteria

- The patient is >= 18 years of age;
- The patient has at least one endosseous implant in the oral cavity with clinical and radiographical signs of peri-implantitis. Peri-implantitis is defined as progressive loss of marginal bone >= 2mm, as compared to the baseline radiograph (after placing the definitive restoration) in combination with bleeding and/or suppuration on probing (Lang and Berglundh 2011);
- The implants have been in function for at least two years;
- The patient is capable of understanding and giving informed consent.

Exclusion Criteria

- Medical and general contraindications for the procedures;
- A history of local radiotherapy to the head and neck region;
- Pregnancy and lactation;
- Uncontrolled diabetes mellitus (HbA1c < 7% or < 53 mmol/mol);
- Use of antibiotics during the last 3 months;
- Known allergy to chlorhexidine;
- Long-term use of anti-inflammatory drugs;
- Incapability of performing basal oral hygiene measures as a result of physical or mental disorders;
- Implants with bone loss exceeding 2/3 of the length of the implant or implants with bone loss beyond the transverse openings in hollow implants;
- Implant mobility;
- Implants at which no position can be identified where proper probing measurements can be performed;
- Previous surgical treatment of the peri-implantitis lesions;
- Previous non-surgical treatment of the peri-implantitis lesions during the last 3 months (scaling or curettage)
- Chronic bronchitis and asthma

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- Mean peri-implant bleeding score (%)<br /><br>- Mean peri-implant and full-mouth periodontal suppuration on probing score (%);<br /><br>- Mean peri-implant and full-mouth periodontal probing pocket depth;<br /><br>- Mean peri-implant and full-mouth periodontal plaque score (%);</p><br>