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Can administration of iron supplement injection reduce blood transfusion rates in people with a low red blood cell count (anaemia) who are undergoing heart operation?

Not Applicable
Completed
Conditions
se of iron supplement injection (Ferinject) in anaemic patients undergoing heart surgery.
Haematological Disorders
Iron deficiency anaemia
Registration Number
ISRCTN22158788
Lead Sponsor
Royal Wolverhampton Hospitals NHS Trust (UK)
Brief Summary

2017 results in British Society of Gastroenterology Annual General Meeting 2017 https://gut.bmj.com/content/66/Suppl_2/A113.2 2019 results in: https://www.ncbi.nlm.nih.gov/pubmed/30107449 (added 14/08/2019)

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
50
Inclusion Criteria

1. Aged 18 years or older
2. Elective cardiac surgery
3. Pre-operative haemoglobin (Hb) level >1g/dl below the normal range (i.e. women <11.5g/dl and men <12.5 g/dl)

Exclusion Criteria

1. Pregnancy
2. Patient participating in another trial
3. Patients unable to give written consent
4. Patients with a recognised allergy or other contraindication to intravenous iron or related products
5. Low haemoglobin attributable to haemoglobinopathy
6. Anaemia secondary to known co-existing and uncorrected B12 or folate deficiency
7. Patients already receiving oral or intravenous iron treatment
8. Patients with evidence of significant symptomatic anaemia which would normally require urgent transfusion at the time of assessment
9. Patients with a Hb less than 9.0 g/dl

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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