Interest of Intensive Postoperative Rehabilitation Following Minimally Invasive Lung Resection

Not Applicable

Not yet recruiting

• Conditions: Lung Cancer
• Interventions: Other: rehabilitation

• Registration Number: NCT06202222
• Lead Sponsor: University Hospital, Rouen

Brief Summary

For patients diagnosed with non-small cell lung cancer (NSCLC), lung resection surgery remains the gold standard for curative treatment. This scheduled operation is associated with significant morbidity, particularly in individuals with impaired cardio-respiratory function. Therefore, patient optimization is paramount. The process begins prior to surgery with preoperative rehabilitation, commonly referred to as "prehabilitation," serving as the foundation for various Enhanced Recovery After Surgery programs. The training methods employed in these programs bear similarity to rehabilitation programs designed for patients with chronic obstructive pulmonary disease (COPD).

Postoperatively, patients undergoing thoracic surgery partake in daily physiotherapy sessions, aiming to optimize the postoperative period, minimize the respiratory impact of surgery, and reduce the length of hospital stay. However, this treatment is not currently standardized and primarily involves early mobilization, including walking, and respiratory physiotherapy. Our focus is on the intensity and methods of this postoperative rehabilitation.

There is limited literature on effective early rehabilitation in the immediate postoperative period, and existing studies suggest no adverse events associated with postoperative training. Therefore, our objective is to assess whether combining endurance training with standard physiotherapy (walking and respiratory physiotherapy) enhances the functional capacity of individuals undergoing lung surgery.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-11
• Study First Submitted: 2023-12-29
• Study First Submitted QC: 2023-12-29
• Study First Posted: 2024-01-11
• Last Update Submitted: 2024-01-15
• Last Update Posted: 2024-01-17
• Study Start: 2024-02-01
• Primary Completion: 2024-02-01
• Study Completion: 2026-09-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 184

Inclusion Criteria

• Patients requiring surgery for diagnosed or undergoing diagnosis of lung cancer.
• Patients in need of major lung resection through a minimally invasive approach.
• Patients capable of performing the chair rise test.

Exclusion Criteria

• Contraindications to cyclo-ergometry: Deep vein thrombosis in a lower limb. Patients with one or both lower limbs amputated. Rheumatological pathology, trauma, or previous surgery in the lower limb, pelvis, or spine, resulting in limited joint amplitude or strict immobilization.

Dermatological conditions with severe lesions preventing prolonged sitting on a bicycle.

• Glasgow score less than 15.
• Patients who have not undergone pulmonary resection by minimally invasive surgery.
• Patients hospitalized outside the thoracic surgery department before the first post-operative visit with the physiotherapist on Day 0.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
standard rehabilitation and cycloergometer	rehabilitation	-

Primary Outcome Measures

Name	Time	Method
Number of chair lifts at the scheduled visit 30 days after surgery	30 days after surgery	number of chair lifts

Secondary Outcome Measures

Name	Time	Method
chair rise test	7 days after surgery
number of complication GRADE II of clavien dindo classification	30 days after surgery
number of days between surgery and discharge patient	30 days after surgery

Trial Locations

Locations (3)

CAEN, university Hospital; 🇫🇷 Caen, Normandie, France

Rouen, University Hospital; 🇫🇷 Rouen, Normandie, France

Valenciennes, Hospital; 🇫🇷 Valenciennes, Hauts De France, France