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Response to SLT vs. ALT in Patients Under 60 Years of Age

Not Applicable
Completed
Conditions
Glaucoma
Interventions
Procedure: Argon laser trabeculoplasty
Procedure: Selective laser trabeculoplasty
Registration Number
NCT01087684
Lead Sponsor
Sunnybrook Health Sciences Centre
Brief Summary

Laser trabeculoplasty is a routine treatment for glaucoma and can be performed with either argon (ALT) or selective Yag (SLT) lasers. The effectiveness of each has not been studied in patients under 60 years, which is younger than average for the procedure. The study hypothesis is that there will be no difference between the two laser types.

Detailed Description

Forty-two young patients (age 29 to 60) had one eye randomized to ALT (n = 22) or SLT (n = 20). Intraocular pressure was measured prior to laser and 1 hour, 1 day, 6 weeks, 3 months, every 3 months until 2 years, and then yearly post-laser. χ2 analysis and student's t-test were used to determine statistical significance.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
42
Inclusion Criteria
  • Age < 60 years
  • Intraocular pressure not adequately controlled
Exclusion Criteria
  • Prior laser treatment

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
Argon laser trabeculoplastyArgon laser trabeculoplastyPatients received standard argon laser treatment
Selective laser trabeculoplastySelective laser trabeculoplastyPatients received a standard selective laser treatment
Primary Outcome Measures
NameTimeMethod
Intraocular pressureTwo years

The intraocular pressure was measured at 6 weeks, 4.5 months, 9, 12, 18 and 24 months following the laser treatment.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Sunnybrook Health Sciences Centre

🇨🇦

Toronto, Ontario, Canada

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