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Advancing methodology for determination of free plasma concentrations of drugs by HPLV-UV after ultrafiltratio

Conditions
Method to determine the plasma protein binding rate of drugs.
Registration Number
DRKS00031635
Lead Sponsor
niversitätsklinikum Regensburg
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
1065
Inclusion Criteria

1. Residual Material can be obtained without intervention at the patient
2. Patient is under therapy with one of the target substances, irrespective of the study, OR a patient with abnormal values of covariates with potential influence to plasma protein binding rate (e.g. albumine)

Exclusion Criteria

n/a

Study & Design

Study Type
observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Determination of the total and free plasma concentrations of drugs (f.i. Vancomycin)
Secondary Outcome Measures
NameTimeMethod
Determination of the influence of certain covariates to plasma protein binding rate.
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