"To Evaluate Efficacy of Dexmedetomidine for Reducing Sucicnylcholine Induced Myalgia in Patients undergoing Electro convulsive Therapy."
Overview
- Phase
- Post Marketing Surveillance
- Status
- Not yet recruiting
- Sponsor
- Dhiraj Hospital Sumandeep vidyapeeth
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- This prospective study will help us to evaluate the efficacy of low dose intravenous Dexmedetomidine in reducing fasciculations and myalgia due to sucicnylcholine during electro convulsive therapy.
Overview
Brief Summary
In the present study we will be comparing the efficacy of low dose of intravenous Dexmedetomidine (0.25 mcg/ kg) diluted in 100 ml Normal Saline for reducing incidence and severity of sucicnylcholine induced myalgia and fascination and optimization of hemodynamics in patients undergoing electro convulsive therapy.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant and Outcome Assessor Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 65.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patients willing to sign informed consent.
- •Patient belonging to ASA physical status 1 and
- •Patients undergoing Electroconvulsive therapy.
Exclusion Criteria
- •Patients unwilling to participate in study.
- •Patient with BMI more than 30 kg/m
- •Patient who are deaf or incapable of understanding the language.
- •Patients with history of allergy to an adrenergic agonist.
- •Pregnancy and lactating women.
Outcomes
Primary Outcomes
This prospective study will help us to evaluate the efficacy of low dose intravenous Dexmedetomidine in reducing fasciculations and myalgia due to sucicnylcholine during electro convulsive therapy.
Time Frame: This prospective study will help us to evaluate the efficacy of low dose intravenous Dexmedetomidine in reducing fasciculations immediately after giving Sccinylcholine and myalgia due to sucicnylcholine after 60 minutes of electro convulsive therapy.
Secondary Outcomes
- Effect of Dexmedetomidine in attenuating blood pressure & heart rate during electro convulsive therapy.(At Base line, 5 min after drug intervention, During ECT, 3 min, 5 min, 10 min, 20 min, 30 min after ECT)
Investigators
DR SUCHETA SUHAS DOSHI
Smt Bhailal Kothari Shah Medical Institute and Research Centre Vadodara, Gujarat.