A Pilot Study to evaluate Failure Patterns after Escalated Dose Radiotherapy to 74 Gy in High Grade Glioma (HGG): A Prospective Study.

Department of Radiotherapy and Clinical Oncology, PGIMER, Chandigarh1 个研究点分布在 1 个国家目标入组 30 人开始时间: 2026年2月1日最近更新: 2025年12月31日

试验速览

阶段: 不适用
状态: 尚未招募
发起方
入组人数: 30
试验地点: 1

研究概览研究设计入排标准研究者研究点记录与标识符相似试验

研究概览

简要总结

Multiple studies have shown that majority of failures in Glioblastomas occur either centrally or within the high dose field. This study aims to see the effects of applying a higher radiation dose (74Gy) to the tumour alongside concurrent chemotherapy to see the failure pattern thereafter.

研究设计

研究类型: Interventional
分配方式: Na
盲法: None

入排标准

年龄范围: 18.00 Year(s) 至 80.00 Year(s)（—）
性别: All

入选标准

•Histologically confirmed post operative cases of High Grade Gliomas including Astrocytoma Grade 3 or Grade 4, Glioblastoma Grade
•Age greater than or equal to 18 years.
•KPS greater than or equal to
•Adequate renal, hepatic and hematologic function.
•Patients willing to participate in the study with written and informed consent.

排除标准

•Previous history of chemoradiation.
•Other primary, recurrent or metastatic disease.
•Patients with significant life-threatening co-morbidities.
•History of acute or chronic liver disease.

研究者

发起方

Department of Radiotherapy and Clinical Oncology, PGIMER, Chandigarh

申办方类型

Research institution and hospital

责任方

Principal Investigator

主要研究者

Dr Chitran Chakrabortty

Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh

研究点 (1)

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