Genetic Disorders of Obesity Program Database
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Obesity, Childhood
- Sponsor
- Baylor College of Medicine
- Enrollment
- 500
- Locations
- 1
- Primary Endpoint
- Prevalence of genetic causes of severe, early-onset obesity
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
This study collects data on children with severe, early-onset obesity.
Detailed Description
Children and adolescents who have suffered from severe weight gain prior to 5 years of age and who are seen in the Genetic Disorders of Obesity Program at Texas Children are asked to participate in a prospective, observational study. The investigators collect demographic information, body measurements, medical/family history, as well as other questionnaires. Additionally, genetic information, medical lab results, and responses to treatment options are collected. The goal of the study is to determine if the investigators can better understand which children would benefit from testing and further workup as well as to understand how obesity develops in these children and adolescents.
Investigators
Stephanie Sisley
Associate Professor
Baylor College of Medicine
Eligibility Criteria
Inclusion Criteria
- •For individuals 2 years and older, BMI \> 97 percentile
- •For individuals \< 2 years old, weight-to-length ratio \> 95th percentile
Exclusion Criteria
- •No other exclusion criteria
Outcomes
Primary Outcomes
Prevalence of genetic causes of severe, early-onset obesity
Time Frame: through study completion, an average of 10 years
We will measure the number of genetic variants identified in clinical testing
Secondary Outcomes
- Change in BMI over time(through participant completion, an average of 2 years)