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Clinical Trials/NCT04949334
NCT04949334
Unknown
Not Applicable

Effects of Respiratory Muscle Training in Patients With Acute Ischemic Stroke

Taipei Medical University Shuang Ho Hospital1 site in 1 country144 target enrollmentSeptember 23, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke, Ischemic
Sponsor
Taipei Medical University Shuang Ho Hospital
Enrollment
144
Locations
1
Primary Endpoint
Respiratory muscle function-1.3
Last Updated
4 years ago

Overview

Brief Summary

After acute ischemic stroke, the muscle strength of the limbs of the patients will decrease. Moreover, the respiratory muscles may also be affected. The respiratory muscle training may improve the respiratory recovery and prevent pulmonary complication.

Detailed Description

After acute ischemic stroke, the muscle strength of the limbs of the patients will decrease. Moreover, the respiratory muscles may also be affected. The worsening of the respiratory function is weakened and lung function declines, leading to dysfunction of expectoration and swallowing, and increasing the incidence of pneumonia after stroke. In addition, it will also lead to a decline in activity ability, which in turn affects the quality of life. The respiratory muscle training may improve the respiratory recovery and prevent pulmonary complication.

Registry
clinicaltrials.gov
Start Date
September 23, 2021
End Date
July 15, 2023
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Taipei Medical University Shuang Ho Hospital
Responsible Party
Principal Investigator
Principal Investigator

Chen ruey

Assistant professor

Taipei Medical University Shuang Ho Hospital

Eligibility Criteria

Inclusion Criteria

  • Ischemic stroke diagnosed by MRI
  • Age over 20 years old
  • No worsening of stroke or second stroke this time

Exclusion Criteria

  • Unable to understand instructions normally, or communication difficulties
  • Patients with endotracheal tube or tracheostomy
  • Angina in recent 3 months, myocardial infarction, heart failure
  • Patients with asthma or chronic obstructive pulmonary disease, spontaneous pneumothorax, and ongoing pneumonia
  • Patients with untreated hernias
  • Ongoing fever (body temperature\>38.5°C)
  • Poor hypertension control (higher than 170/100 mmHg three days before intervention)
  • Patients who have had cerebral hemorrhage or aneurysm

Outcomes

Primary Outcomes

Respiratory muscle function-1.3

Time Frame: Twelve weeks after training

MEP (maximal expiratory pressure)

Respiratory muscle function-1.1

Time Frame: Baseline

MEP (maximal expiratory pressure)

Respiratory muscle function-1.2

Time Frame: Within one week after training

MEP (maximal expiratory pressure)

Respiratory muscle function-2.2

Time Frame: Within one week after training

MIP (maximal inspiratory pressure)

Respiratory muscle function-2.1

Time Frame: Baseline

MIP (maximal inspiratory pressure)

Respiratory muscle function-2.3

Time Frame: Twelve weeks after training

MIP (maximal inspiratory pressure)

Secondary Outcomes

  • Exercise tolerance.1(Baseline)
  • Dyspnea.2(Within one week after training)
  • Exercise tolerance.3(Twelve weeks after training)
  • Life quality.2(Within one week after training)
  • Life quality.3(Twelve weeks after training)
  • Body composition.3(Twelve weeks after training)
  • Swallowing.2(Within one week after training)
  • Swallowing.3(Twelve weeks after training)
  • Body composition.2(Within one week after training)
  • Life quality.1(Baseline)
  • Swallowing.1(Baseline)
  • Dyspnea.1(Baseline)
  • Exercise tolerance.2(Within one week after training)
  • Body composition.1(Baseline)
  • Dyspnea.3(Twelve weeks after training)

Study Sites (1)

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