Effects of Respiratory Muscle Training in Patients With Acute Ischemic Stroke
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 144
- 试验地点
- 2
- 主要终点
- Respiratory muscle function-1.3
研究概览
简要总结
After acute ischemic stroke, the muscle strength of the limbs of the patients will decrease. Moreover, the respiratory muscles may also be affected. The respiratory muscle training may improve the respiratory recovery and prevent pulmonary complication.
详细描述
After acute ischemic stroke, the muscle strength of the limbs of the patients will decrease. Moreover, the respiratory muscles may also be affected. The worsening of the respiratory function is weakened and lung function declines, leading to dysfunction of expectoration and swallowing, and increasing the incidence of pneumonia after stroke. In addition, it will also lead to a decline in activity ability, which in turn affects the quality of life. The respiratory muscle training may improve the respiratory recovery and prevent pulmonary complication.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Ischemic stroke diagnosed by MRI
- •Age over 20 years old
- •No worsening of stroke or second stroke this time
排除标准
- •Unable to understand instructions normally, or communication difficulties
- •Patients with endotracheal tube or tracheostomy
- •Angina in recent 3 months, myocardial infarction, heart failure
- •Patients with asthma or chronic obstructive pulmonary disease, spontaneous pneumothorax, and ongoing pneumonia
- •Patients with untreated hernias
- •Ongoing fever (body temperature>38.5°C)
- •Poor hypertension control (higher than 170/100 mmHg three days before intervention)
- •Patients who have had cerebral hemorrhage or aneurysm
结局指标
主要结局
Respiratory muscle function-1.3
时间窗: Twelve weeks after training
MEP (maximal expiratory pressure)
Respiratory muscle function-1.1
时间窗: Baseline
MEP (maximal expiratory pressure)
Respiratory muscle function-1.2
时间窗: Within one week after training
MEP (maximal expiratory pressure)
Respiratory muscle function-2.2
时间窗: Within one week after training
MIP (maximal inspiratory pressure)
Respiratory muscle function-2.1
时间窗: Baseline
MIP (maximal inspiratory pressure)
Respiratory muscle function-2.3
时间窗: Twelve weeks after training
MIP (maximal inspiratory pressure)
次要结局
- Exercise tolerance.1(Baseline)
- Dyspnea.2(Within one week after training)
- Exercise tolerance.3(Twelve weeks after training)
- Life quality.2(Within one week after training)
- Life quality.3(Twelve weeks after training)
- Body composition.3(Twelve weeks after training)
- Swallowing.2(Within one week after training)
- Swallowing.3(Twelve weeks after training)
- Body composition.2(Within one week after training)
- Life quality.1(Baseline)
- Swallowing.1(Baseline)
- Dyspnea.1(Baseline)
- Exercise tolerance.2(Within one week after training)
- Body composition.1(Baseline)
- Dyspnea.3(Twelve weeks after training)
研究者
Chen ruey
Assistant professor
Taipei Medical University Shuang Ho Hospital