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Clinical Trials/NCT05682963
NCT05682963
Completed
Not Applicable

Effect of Square- Stepping Exercises on Mobility, Balance and Knee Joint Position Sense in Individuals With Multiple Sclerosis

Pamukkale University1 site in 1 country34 target enrollmentNovember 29, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Multiple Sclerosis
Sponsor
Pamukkale University
Enrollment
34
Locations
1
Primary Endpoint
Timed 25-Foot Walk (T25-FW) Test
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

Square stepping exercises can promote correct foot placement, fast and coordinated step patterns, and sensory-motor interaction. The aim of this study is to examine the effect of square stepping exercises on mobility, balance and knee joint position sense in individuals with multiple sclerosis.

Detailed Description

Multiple sclerosis (MS) is a chronic, inflammatory, autoimmune disease of the central nervous system that results in neurological disability. Complex gene-environment interactions play a role in the etiology of multiple sclerosis. Multiple sclerosis is more common in women than men, with a ratio ranging from 2:1 to 3:1. MS is a very heterogeneous disease and it can have very variable clinical signs and symptoms, including motor, sensory, autonomic and cognitive disorders, depending on the region of the central nervous system. Balance and mobility disorders are the leading symptoms of MS. In addition, somatosensory disorders are frequently encountered as the initial symptom. Disorders in position sense, which is one of the components of somatosensory sense, is an important determinant of limitations during dynamic activities such as walking and balance. In order to reduce disability and improve function in individuals with Multiple Sclerosis, square stepping exercises protocol will be given to one group and a home exercise program protocol to the other group. Created by Shigematsu and Okura to improve balance and reduce the risk of falling, the square stepping exercises is performed on a thin exercise mat divided into 40 small squares of 250 cm x 100 cm. There are a number of step patterns that must be followed by the participants. Certain step patterns will be repeated 3-5 times to the participants and the participant will be asked to repeat the same pattern. As a home exercise protocol, a program consisting of frenkel exercises developed by Professor Heinrich Sebastian Frenkel for the treatment of gait, balance and coordination will be applied. Square stepping exercises can promote correct foot placement, fast and coordinated step patterns, and sensory-motor interaction. The aim of this study is to examine the effect of square stepping exercises on mobility, balance and knee joint position sense in individuals with multiple sclerosis.

Registry
clinicaltrials.gov
Start Date
November 29, 2022
End Date
December 25, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

müge içelli

lecturer

Pamukkale University

Eligibility Criteria

Inclusion Criteria

  • Having a disability score of less than 4
  • Being between 20-50 years old
  • Not having an attack in the last month
  • Patients without lower extremity spasticity according to Modified Ashworth Scale (MAS)

Exclusion Criteria

  • Having a neurological disease other than Multiple Sclerosis
  • Having an Multiple Sclerosis attack during the study
  • Having had orthopedic surgery affecting balance
  • Presence of cognitive and psychiatric influences that will affect participation in the study
  • Having a cardiovascular or pulmonary history that would inhibit participation in the study
  • Have received steroid and/or immunosuppressive therapy in the past four weeks

Outcomes

Primary Outcomes

Timed 25-Foot Walk (T25-FW) Test

Time Frame: 8 weeks

With the Timed 25-Foot Walk (T25-FW) Test, the patient's walking speed and lower extremity functions are evaluated. The patient is asked to walk a distance of 7.62 m (25 feet) safely and as quickly as possible. The passing time is recorded in seconds with the chronometer. The T25-FW is the best-defined measurement method for the measurement of gait disturbance in patients with MS and the evaluation of gait speeds of patients with many gait disorders in the clinical setting.

Secondary Outcomes

  • Five Times Sit to Stand Test(8 week)
  • Activity-Specific Balance Confidence Scale(8 week)
  • Knee Joint Position Sense(8 week)
  • Expanded Disability Status Scale (EDSS)(8 week)
  • Four Step Square Test (FSST)(8 week)

Study Sites (1)

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