Efficacy of two-dose methotrexate therapy in ectopic pregnancy
Not Applicable
- Conditions
- Ectopic pregnancy.Ectopic pregnancy, unspecified
- Registration Number
- IRCT2015080523519N1
- Lead Sponsor
- Ahwaz Jundishapur University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 76
Inclusion Criteria
stable hemodynamic condition;
low free fluid intrapritoneal on ultrasound; BHCG less than 15000 mU/mL; no history of liver or renal disease or blood dyscrasia; no breastfeeding and patient satisfaction.
Exclusion criteria: unwillingness to continue participation in the study; unstable hemodinamic condition.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The overall success(15% reduction in ß-HCG level ). Timepoint: At days: 4 and 7. Method of measurement: Lab test.
- Secondary Outcome Measures
Name Time Method The time BHCG reached 200 mU/mL. Timepoint: daily. Method of measurement: Lab test.;Side effects. Timepoint: 7 days after treetment. Method of measurement: If liver trans aminase increased 1.5 times more than normal, or creatinine increased to 1.5mg/dL, WBCs decreased to 2000 or platelets declined fewer than 100000, these were assumed as drug complications.;The rate of surgery. Timepoint: During the follow-up period. Method of measurement: If the rupture of fallopian tube has happened, patient underwent the immediate surgery.