Improving Functional Capacity in Heart Failure Patients Supported With Continuous-flow Left Ventricular Assist Devices. -Effects of Increased Pump Speed During Sustained Submaximal Exercise
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Heart Failure
- Sponsor
- Rigshospitalet, Denmark
- Enrollment
- 31
- Locations
- 1
- Primary Endpoint
- Exercise time
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
This randomized trial has been designed to study if it is possible to enhance work capacity during submaximal efforts in heart failure patients supported with continuous-flow left ventricular assist devices (CF-LVAD).
The hypothesis is that exercise tolerability during low to moderate workloads in CF-LVAD patients can be increased when pump speed is increased soon after the onset of exercise.
Detailed Description
To test the hypothesis described above the investigators will study submaximal exercise tests below anaerobic threshold in patients supported with CF-LVADs.Each patient will perform two tests- one with baseline CF-LVAD pump speed and the other with incrementally increased pump speed.
Investigators
Finn Gustafsson
MD
Rigshospitalet, Denmark
Eligibility Criteria
Inclusion Criteria
- •Ischemic and non-ischemic cardiomyopathy patients with CF-LVADs,signed informed consent.
Exclusion Criteria
- •Unstable patients, CF-LVAD implantation less than three months ago.
Outcomes
Primary Outcomes
Exercise time
Time Frame: Exercise time will be estimated only on the day of the study. No follow-up.
Exercise will be performed on a upright ergometer bike with simultaneously breath-by-breath gaz analysis.
Secondary Outcomes
- Perceived exertion(Perceived exertion will be estimated during exercise on the ergometer bike on the day of the study.)