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临床试验/NCT00842413
NCT00842413
终止
不适用

What Part Does the Premotor Cortex Play in Subjective Visual Perception and in the Perception of Others' Actions?

Assistance Publique - Hôpitaux de Paris1 个研究点 分布在 1 个国家目标入组 9 人2007年5月

概览

阶段
不适用
干预措施
未指定
疾病 / 适应症
Brain Injury
发起方
Assistance Publique - Hôpitaux de Paris
入组人数
9
试验地点
1
状态
终止
最后更新
17年前

概览

简要总结

This project aims at understanding better the role of the frontal lobe of the brain in our capacity to perceive visual information consciously, and also, in our capacity to perceive others' actions. It includes a test where we ask subjects to detect visual information in front of a computer screen, and another test where we ask them to imitate finger movements.

详细描述

This project is a twofold exploration of the functions of the premotor cortex, concerning, on the one hand, its role in conscious visual perception, and on the other hand, the part it may play in the perception and imitation of other people's movements. Healthy subjects will be compared with subjects suffering from focal lesions within the premotor cortex, on two tasks: in the first task, the subjects will have to make a decision concerning the absence or presence of a visual item in their field of vision. They will make (virtual) bets based on the subjective certainty of their perceptions - they will be told that these bets are purely virtual, and will not result in any financial gain or loss. This study will help us understand the contribution of the prefrontal cortex to subjective weighing of perceptual certainty. In the second task, the subjects will imitate a finger movement, based either on a fixed picture, or on a short motion picture. Previous studies have shown that whether the movement is copied from a fixed picture or a moving picture changes reaction times and types of mistakes. Neuroimaging studies have shown that a premotor area is involved in this effect. The comparison of brain-damaged and healthy subjects will tell us what exactly the contribution of the prefrontal consists in.

注册库
clinicaltrials.gov
开始日期
2007年5月
结束日期
2007年9月
最后更新
17年前
研究类型
Observational
性别
All

研究者

入排标准

入选标准

  • Healthy subjects chosen from a pool of adult subjects, recruited through ads.
  • In the second group, the subjects are recruited from a pool of brain-damaged patients treated at the hospital de la Pitié-Salpétrière. They must suffer from a focal lesion in the prefrontal cortex.

排除标准

  • For the healthy group: any previous brain-related medical history.
  • Widespread brain-damage, extending beyond the prefrontal cortex, that is to say, lesions that are not really focal.

结局指标

主要结局

未指定

研究点 (1)

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