comparative evaluation of the effect of misoprostol vaginal suppository to vaginal misoprostol with nitroglycerine in rippening of cervix in term pregnancy reffered to kowsar hospital

Phase 2

• Conditions: Ripening cervix.

• Registration Number: IRCT20120428009576N4
• Lead Sponsor: Qazvin University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 February 2020

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 106

Inclusion Criteria

Primigravida
Gestational age>=37 week
Bishop score<=4
Cephalic presentation
Reactive NST
Viable fetus
Estimated weight before 4 kilogram
Amniotic fluid >5
Singleton

Exclusion Criteria

Surgery on the uteus or previous cesarean section
chronic hypertension and preeclampsia
uterine contractions
The presence of heart, kidney and liver disease
rapture of membrane
IUGR
Suspected embryonic anomalies
chorioamnionitis
Fever above 38 ° C
polyhydramnios
Pre-delivery hemorrhage
fetal distress

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The duration of cervical ripening until delivery. Timepoint: 6 and 12 hours. Method of measurement: Vaginal exam.

Secondary Outcome Measures

Name	Time	Method
Duration of taking the drug until the onset of the active phase of labor. Timepoint: every 2 hours. Method of measurement: Vaginal exam.;Duration of taking drug until delivery. Timepoint: every 2 hours. Method of measurement: Vaginal exam.;Duration of the fist phase of labor. Timepoint: every 2 hours. Method of measurement: Vaginal exam.;Duration of the second phase of labor. Timepoint: every 1 hours. Method of measurement: Vaginal exam.;Reach to vaginal delivery. Timepoint: After delivery. Method of measurement: Date sheet.;Type of delivery. Timepoint: After delivery. Method of measurement: Date sheet.