A randomised, double-blind controlled trial of mometosone furoate cream versus placebo to prevent radiation dermatitis of the breast and chest wall

Phase 3

Completed

• Conditions: Topic: National Cancer Research Network; Subtopic: Breast Cancer; Disease: Breast; Signs and Symptoms; Radiation dermatitis

• Registration Number: ISRCTN03885092
• Lead Sponsor: ancashire Teaching Hospitals NHS Trust (UK)

Brief Summary

2014 Results article in https://doi.org/10.1016/j.ijrobp.2014.06.033 (added 24/01/2022)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-07-07
• Study Completion: 2011-07-31
• Last Update Posted: 7 February 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

1. Aged 18 years or over, either sex
2. Receiving 40 Gy 15 fractionated, 3 week radical radiotherapy to the breast or chest wall
3. Patient provides informed consent to participate in the study and completes follow up

Exclusion Criteria

1. Skin involvement of disease
2. Untreated bacterial, fungal or viral skin lesions
3. Inability to self administer creams

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change in visual skin assessment

Secondary Outcome Measures

Name	Time	Method
<br> 1. Objective skin assessment<br> 2. Changes in quality of life measures<br>