Examining a Fast Movement Approach to Pediatric Therapy Intervention in Children and Adolescents That Have Completed Medical Treatment for Acute Lymphoblastic Leukemia
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Childhood Cancer
- Sponsor
- University of Maryland, Baltimore
- Enrollment
- 10
- Locations
- 1
- Primary Endpoint
- Gross Motor Proficiency
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
Acute lymphoblastic leukemia (ALL) is the most common pediatric malignancy, with the peak incidences occurring in children two to five years of age. Children with ALL received neurotoxic chemotherapy agents for two to three years that causes decreased distal muscle strength and poor timing of muscle activation. After completion of medical treatment, ALL childhood cancer survivors (ALL CCS) are more likely to have an inactive lifestyle, resulting in life-long gross motor proficiency differences compared to their peers. ALL CCS typically do not utilize physical therapists' expertise after medical treatment has been completed. There are limited physical therapy (PT) intervention studies for ALL CCS.
Detailed Description
We are performing a feasibility study to examine a movement based intervention that utilizes fast movements through jumping rope to improve balance, coordination, movement speed, and movement agility. The abilities to generate fast movements are required to perform functional activities and for playing sports. Participants will receive five in-person PT sessions and a home program for six weeks. The goal of this research is to determine the feasibility, acceptability, and promise of a PT program that emphasizes fast movements in ALL CCS.
Investigators
victoria marchese
Associate Professor, Chair
University of Maryland, Baltimore
Eligibility Criteria
Inclusion Criteria
- •Children 6-17 years old
- •Completed medical treatment for ALL within the past five years (1 to 60 months)
- •Speak English.
Exclusion Criteria
- •Diagnosis of a neurological disorder such as cerebral palsy, Down syndrome
- •Currently receiving PT services.
Outcomes
Primary Outcomes
Gross Motor Proficiency
Time Frame: 20 minutes
Bruininks-Oseretsky Test of Motor Proficiency 2nd edition (BOT-2) (subtest 4, 5, 6, 8: bilateral coordination, balance, running speed and agility, and strength). The BOT-2 is a reliable and valid norm-referenced instrument designed for children and adolescents 4-21 years old.
Secondary Outcomes
- Peak vertical ground reaction(5 minutes)
- Motion Capture Analysis(5 minutes)
- Children's Assessment of Participation and Enjoyment (CAPE) questionnaire.(10 minutes)
- Preferences for Physical Activity for Children (PAC)(10 minutes)
- electromyography (EMG)(5 minutes)
- Vertical Jump Height(5 minutes)