Postoperative cognitive dysfunction follwing ophthalmic surgery in visually impaired patients

• Conditions: Postoperative cognitive dysfunction; H54; Visual impairment including blindness (binocular or monocular)

• Registration Number: DRKS00014334
• Lead Sponsor: niversitätsklinikum Jena Klinik für Anästhesiologie und Intensivmedizin

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-03-26
• Study Completion: 2019-03-01
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 105

Inclusion Criteria

Age >65 years
Visually impairment and schedue for ophthalmic surgery (Pars plana Vitrectomy)
Absence of preoperative cognitive impairment
<7 points on 6CIT scale

Exclusion Criteria

Age <65 years
preoperative cognitive impairment
CIT >7 points
Known dementia
Neurologic disease with cognitive impairment
Cerebral insult <3 months prior study inclusion

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the influence of a short term anaesthesia (60 to 90 minutes) on cognitive function in visually impaired patients<br><br>Tests:<br>- 6-CIT -- Six Cognitive Item Test -- Screnning on preoperative cognitive dysfunction<br>- MoCA blind: Montreal Cognitive Assessment for the blind<br>- CFQ: Cognitive failure questionnaire<br><br>MoCA and CFQ will be applied to detect POCD. Both tests will be performed the day before surgery, on postoperative day 3 and 2-3 weeks after surgery.

Secondary Outcome Measures

Name	Time	Method
Applying tests (in detail the MoCA-blind and CFQ), designed for visually impaired patients to evaluate postoperative cognitive dysfunction