Dose reduction of CT perfusion in patients with acute stroke by optimizing the timing of acquisition time

• Conditions: I64; Stroke, not specified as haemorrhage or infarction

• Registration Number: DRKS00023941
• Lead Sponsor: Klinikum der Universität München, Campus Großhadern

Brief Summary

Conclusions In conclusion, the timing information of the bolus tracking of previous carotid CT angiography can be used in the stroke protocol to reduce radiation exposure by avoiding unnecessary scans. In addition, the information from bolus tracking allows for the better timing of CTP, which could lead to better outcomes in certain cases by adjusted timing.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-07-28
• Results First Posted: 2022-12-01
• Study Completion: 2023-12-28
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

Patients with symptoms of an acute stroke receiving non enhanced cranial CT, CT angiography of the carotid aretry including an archived bolus tracking serie and a CT perfusion on the institutional CT scanner Somatom Force Siemens Healthineers.
Patients with documented acut ischemic stroke.

Exclusion Criteria

Non valid CT perfusion.
Significant altered fluss injection rate of contrast agent in CT perfusion and CT angiography of the carotid artery.

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction of radtion exposure by 20 %.

Secondary Outcome Measures

Name	Time	Method
In the qualitative evaluation of dose reduced simulated CT perfusion examinations, the lowering of the number of scans should have no significant influence on „change of management for patient care.