Diagnosis of Pulmonary Embolism in Pregnancy (DiPEP)

Not Applicable

Completed

• Conditions: Pulmonary embolism in pregnancy; Circulatory System; Pulmonary embolism

• Registration Number: ISRCTN21245595
• Lead Sponsor: Sheffield Teaching Hospital NHS Foundation Trust (UK)

Brief Summary

1. 2018 results in https://www.ncbi.nlm.nih.gov/pubmed/29359796 2. 2018 results in https://www.ncbi.nlm.nih.gov/pubmed/29782079 3. 2018 results in https://www.ncbi.nlm.nih.gov/pubmed/30178738

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2014-07-14
• Study Completion: 2017-03-31
• Last Update Posted: 24 September 2018

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 420

Inclusion Criteria

1. Pregnant and postpartum women with diagnosed PE from all UK hospitals over 18 months
2. Pregnant and postpartum women with suspected PE or diagnosed DVT from 8 hospitals over 18 months

Exclusion Criteria

1. Women who did not present with suspected PE
2. Women who are unable to consent, requiring resuscitation or with an existing diagnosis of PE

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Pulmonary embolism (PE)<br>2. Cost-effectiveness<br>The outcome for diagnostic accuracy (case-control) study will be diagnosis of PE based on diagnostic imaging and any adverse events up to 30 days. The outcome for the cost-effectiveness analysis will be life-time quality-adjusted life years (QALYs), estimated by decision analysis modelling.