The Model for End-Stage Liver Disease Sodium (MELD-Na) Score in Non-cirrhotic Patients With Gastric Cancer

Completed

• Conditions: Complications; Gastrointestinal, Postoperative; Gastric Cancer; Complication,Postoperative; Morality
• Interventions: Other: MELD-Na score

• Registration Number: NCT04791293
• Lead Sponsor: Istanbul Training and Research Hospital

Brief Summary

Gastric cancer is the fifth most common cancer worldwide. Gastrectomy with lymphadenectomy is still the most effective treatment modality, depending on the stage and location. Despite many radiological, surgical and anesthetic innovations, serious complications such as anastomotic leakage, intra-abdominal abscesses, wound complications are seen secondary to gastrectomy. Many clinical studies have been conducted to prevent and predict these complications.

The Model for End-Stage Liver Disease (MELD) score, in which bilirubin, international normalized ratio (INR) and serum creatinine values were used to determine surgical risks in patients scheduled for liver transplantation. Latter developed by adding serum sodium (Na) to the formula. The MELD-Na score is used to predict postoperative complications in non-cirrhotic patients because of its simple and easy calculation.Moreover, The Meld-Na score was later used to predict complications for surgical procedures other than liver surgery such as colorectal surgery.

In this study, we aimed to investigate the importance of the Meld-Na score in predicting the perioperative and postoperative outcomes in patients with gastric cancer.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-12-01
• Study First Submitted: 2021-03-06
• Study First Submitted QC: 2021-03-06
• Study First Posted: 2021-03-10
• Status Verified: 2022-08
• Primary Completion: 2022-08-05
• Study Completion: 2022-08-05
• Last Update Submitted: 2022-08-05
• Last Update Posted: 2022-08-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 159

Inclusion Criteria

• Patients undergoing gastrectomy due to gastric cancer

Exclusion Criteria

• Patients with pulmonary, hepatic and renal disfunctions,
• Patients with diagnosed with a different cancer in the last 5 years and
• Pregnant patients

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Group 2	MELD-Na score	Patients without postoperative complications
Group 1	MELD-Na score	Patients with postoperative complications

Primary Outcome Measures

Name	Time	Method
MELD-Na score difference between the groups	30 days	Importance of MELD-Na score in predicting postoperative complications in patients with gastric cancer

Trial Locations

Locations (1)

Istanbul Training and Research Hospital; 🇹🇷 Istanbul, Turkey