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Clinical Trials/NCT05443737
NCT05443737
Recruiting
Phase 3

Evaluation of a Telehealth Oncofertility Care Intervention in Adolescent and Young Adult Cancer Patients: a Stepped Wedge Cluster Randomized Controlled Trial

University of California, San Diego4 sites in 1 country2,800 target enrollmentJanuary 1, 2022

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Cancer
Sponsor
University of California, San Diego
Enrollment
2800
Locations
4
Primary Endpoint
Decisional Conflict
Status
Recruiting
Last Updated
5 months ago

Overview

Brief Summary

The purpose of this study is to evaluate the effectiveness of a multi-component intervention to improve young cancer survivors' engagement in goal-concordant oncofertility care, concurrently with observing and gathering information on how the intervention is implemented. The investigators hypothesize that implementation of the intervention will result in increased young cancer survivors' engagement in goal-concordant oncofertility care.

Registry
clinicaltrials.gov
Start Date
January 1, 2022
End Date
August 31, 2027
Last Updated
5 months ago
Study Type
Interventional
Study Design
Sequential
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Hui-Chun Irene Su

Professor

University of California, San Diego

Eligibility Criteria

Inclusion Criteria

  • Newly diagnosed cancer or cancer relapse
  • Primary language English or Spanish
  • Receiving oncology care at participating clinical sites
  • Ages 0 to 42 years if female
  • Ages 0 to 50 years if male

Exclusion Criteria

  • Non-melanoma skin cancer, because primary treatment is excision with no infertility risk
  • Metastatic/Stage IV non-thyroid solid tumors, because of poor prognosis

Outcomes

Primary Outcomes

Decisional Conflict

Time Frame: 12 weeks after oncology visit

The 16-item Decisional Conflict Scale (DCS) will be used to measure patients' decisional conflict for engaging in fertility preservation services. The DCS consists of 16 statements with 5 response options (ranging from strongly agree to strongly disagree) that measures the patient's perceptions of uncertainty in choosing options, feeling informed, values clarity, support in decision making, and effective decision making. The DCS total score will be dichotomized at 37.5 (scale 0-100; \> 37.5 indicates high decisional conflict).

Number of reproductive-aged female and male patients (aged 12 to 39 years) who engage in goal-concordant oncofertility care

Time Frame: 12 weeks after oncology visit

The proportion of eligible reproductive-aged male and female patients (aged 12 to 39 years) who engage in oncofertility services (1\| an oncofertility needs screen, 2\| referral to oncofertility consult, 3\| oncofertility consult, and/or 4\| fertility preservation services) that meet the patient's individual needs will be abstracted from medical records using standardized case report forms.

Secondary Outcomes

  • Number of female (aged 0 to 42 years) and male (aged 0 to 50 years) patients who engage in goal-concordant oncofertility care(12 weeks after oncology visit)
  • Number of female patients (aged 0 to 42 years) who engage in goal-concordant oncofertility care(12 weeks after oncology visit)
  • Number of male patients (aged 0 to 50 years) who engage in goal-concordant oncofertility care(12 weeks after oncology visit)

Study Sites (4)

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