Physical Activity, Functional Fitness and Quality of Life After Coronary Artery Bypass Grafting

Completed

• Conditions: Coronary Artery Bypass Graft

• Registration Number: NCT01591642
• Lead Sponsor: Far Eastern Memorial Hospital

Brief Summary

The main purposes of this study are: (1) to investigate the difference of the physical fitness, and quality of life (QOL) among different physical activity levels in post-coronary artery bypass graft (CABG) patients; (2) to analyze the relationships between physical activity and physical fitness and QOL in this population. The investigators predict physical activity and physical fitness remain limited in patients after CABG, and patients with higher physical activity levels will have higher QOL and physical fitness.

Detailed Description

Heart diseases continue as the top 3 causes of death in Taiwan in recent ten years. Coronary artery disease (CAD) is the most prevalent fatal heart disease. Coronary artery bypass graft surgery (CABG) is now one of the most common procedures to treat CAD. It was reported that CABG intervention could prolong the life. However, outcomes of CABG have historically been measured in terms of mortality and recurrence of symptoms or complications.There is ample evidence to demonstrate the effect and benefit of cardiac rehabilitation in QOL and function activity in patients post CABG. However, the participation rate of postoperative cardiac rehabilitation is low, especially in women.Little research has been done to examine the physical activity, physical performance, and QOL in this population outside the cardiac rehabilitation setting.

Study Timeline

• Status Verified: 2010-10
• Study Start: 2011-01
• Primary Completion: 2011-12
• Study Completion: 2011-12
• Study First Submitted: 2012-04-27
• Study First Submitted QC: 2012-05-02
• Last Update Submitted: 2012-05-02
• Study First Posted: 2012-05-04
• Last Update Posted: 2012-05-04

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 315

Inclusion Criteria

• patients undergoing CABG without valve surgery

Exclusion Criteria

1. systemic disease, such as liver, renal disease,
2. amputation,
3. cerebrovascular disease or any others disease with limbs dysfunction,
4. lung deficit,
5. cancer,
6. cognitive disorders.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
physical activity	The participants were followed at one time points after operation in past 10 years	The level of physical activity was evaluated by the self-administrated long form of the International Physical Activity Questionnaire, which was permitted by the Bureau of Health Promotion, Department of Health, R.O.C.(Taiwan). It is an instrument that estimates the weekly time spent on the performance of physical activities according to intensity, in different contexts of life (workplace, household tasks, transport and leisure). Reported minutes per week in each category were weighted by a metabolic equivalent (MET; multiples of resting energy expenditure).

Secondary Outcome Measures

Name	Time	Method
physical fitness	The participants were followed at one time points after operation in past 10 years	Physical fitness The outcome measures of physical fitness included body mass index(BMI), waist circumference(WC), grip strength, 30-second chair stand test, and six-minute walk test(6MWT).
quality of life	The participants were followed at one time points after operation in past 10 years	QOL was measured using abbreviated version of the World Health Organization Quality of Life (WHOQOL-BREF) questionnaire. The original WHOQOL-BREF comprised 26 questions and included four domains: physical, psychological, social relationships, and environment. The WHOQOL-BREF scale has been adapted for Taiwan and added two questions appropriate for Taiwanese culture.