Intrauterine Flushing With Follicular Fluid Plus Granulosa Cells

Phase 3

Recruiting

• Conditions: N97.9; Infertile women with male factor.; Female infertility, unspecified

• Registration Number: IRCT20080831001141N29
• Lead Sponsor: ROYAN Institute

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 5 January 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 140

Inclusion Criteria

Normal Hormonal profile (FSH, LH, AMH) and normal AFC
Normal ovarian reserve
Age 20-38 years
Regular menstrual cycle
IVF / ICSI or IVF or ICSI cycles with Agonist Protocol
Existence of at least 2 oocytes in dominant follicular fluids

Exclusion Criteria

Presence of Endometriosis and Endometrioma
Hydrosalpinx
OHSS (Ovarian Hyper Stimulating Syndrome)
Tubal factor infertility
Age <38 years old
Male factor infertility with azoospermia
Low/Poor Response
Myoma with a compression effect or submocusa myometrium
Intra mural or subserouse Myoma > 5cm
Presence of untreated Thyroid, Diabetic and Hepatitis diseases, vaginal infection
Endometrial tuberculosis
Patients with any special drug intake
The follicular fluid which contains any oocyte or contaminated with blood will be discarded

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Evaluation of implantation rate. Timepoint: Only once, day 35-42 post ovum pick-up. Method of measurement: Based on the number of gestational sacs observed, divided by the number of embryos transferred.

Secondary Outcome Measures

Name	Time	Method
Clinical pregnancy rate. Timepoint: Only once; 6 weeks after embryo transfer. Method of measurement: Vaginal ultrasound.