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Motor Evoked Potential in the Affected Upper Limb Predicts the Potential of Motor Recovery in Subacute Stroke Patients

Completed
Conditions
Stroke, Subacute
Interventions
Diagnostic Test: MEPs induced by TMS
Registration Number
NCT03243318
Lead Sponsor
Hospital Authority, Hong Kong
Brief Summary

Stroke is the third common cause of adult disability in dveloped countries. Early identification of the potential for motor recovery is important to avoid 'learned disuse' and to initiate appropriate therapy with achievable goals. The current cohort study focuses on those patients with SAFE \<8 and using motor evoked potentials (MEPs) to improve on prognostication of upper limb motor recovery among subacute stroke patients in a local stroke population.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
32
Inclusion Criteria
  • First stroke with hemiparesis or hemiplegia with SAFE <8
Exclusion Criteria
  • contra-indication to TMS or MRI, history of seizure, pregnancy and mentally unfit to understand the consent

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Presence of motor evoked potentialsMEPs induced by TMSThose patients with Shoulder Abduction and Finger Extension (SAFE) score \<8/10 with the presence of motor evoked potentials elicited by TMS over the ipsilesional motor cortex
absence of motor evoked potentialsMEPs induced by TMSThose patients with Shoulder Abduction and Finger Extension (SAFE) score \<8/10 with the absence of motor evoked potentials elicited by TMS over the ipsilesional motor cortex
Primary Outcome Measures
NameTimeMethod
Action Research Arm TestChange of Baseline Action Research Arm Test at 12 weeks post-stroke

Upper limb functional test

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Department of Rehabilitation, Kowloon Hospital

🇭🇰

Hong Kong, Hong Kong

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