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临床试验/CTRI/2024/04/066158
CTRI/2024/04/066158尚未招募不适用

Perfusion index versus conventional method for determining success of Ultrasound guided supraclavicular brachial plexus block


Velammal Medical College and Research Institute1 个研究点 分布在 1 个国家目标入组 125 人开始时间: 2024年5月8日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
125
试验地点
1
主要终点
The prediction of success or failure of supraclavicular block is early when compared to conventional method.

研究概览

简要总结

Introduction

Supraclavicular nerve block is a popular approach for anaesthesia for upper limb surgeries. Conventional methods for evaluation of block success are time consuming and need patient cooperation.

 Aim

The aim of this study is to evaluate whether the perfusion index (PI) can be used to predict and provide a cut-off value for ultrasound-guided supraclavicular nerve block success.

 Primary objective

To compare the conventional method with perfusion index

Secondary objective

To predict the cut off value for perfusion index

Inclusion  criteria

Patients aged between 18 and 60 yr who were to undergo elective upper limb orthopaedic procedures under ultrasound-guided supraclavicular nerve block.

Exclusion criteria were Allergy to drug,Infection,Coagulopathy

 Methodology

Prospective observational study Sample  size 100 patients

The supraclavicular nerve block has to be done under usg guidance of a linear transducer over the supraclavicular fossa in the coronal oblique plane immediately superior to the midclavicular point.Patient in semi-sitting position, with the head of the patient turned away from the side to be blocked.

 A 22-gauge insulated block needle is in-plane (lateral to medial) to the ultrasound probe. The brachialplexus  will be identified as a compact group of nerves, hypo-echoic, round or oval, located lateral and superficial to the pulsatile subclavian artery and superior to the first rib. A volume of 20ml of localanaesthetic(bupivacaine 0.5%, 10ml and lidocaine 2%, 10 ml) is  injected under vision strictly perineural to surround all the nerve cords.

 The limb is evaluated for block success every 3 min for the sensory block and every 5 min for the motor block. Sensory function is assessed using pinprick in the dermatomal areas supplied by the four main nerves (median nerve, radial nerveulnar nerve, and musculocutaneous nerve). Motor block assessed by the ability to flex the elbow and the hand against gravity.

 The supraclavicular nerve block is considered successful with regard to neurologicalexaminationwhen brachial plexus dermatomes (C5–T1) were completely blocked.

 The PI  is measured using pulse oximetry applied on the index finger. The PI will be recorded at baseline and at 10, 20, and 30 min after local anaesthetic injection in both the blocked limb and the contralateral unblocked limb using two separate oximeters. The PI ratio is  calculated as the ratio between the PI at 10 min after injection and the baseline PI. In every patient, a comparison between the blocked and unblocked limb is  performed.

 Expected outcome

PI when compared to compared to conventional may provide better block success

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Patients aged between 18 and 60 yr Undergoing elective upper limb orthopaedic procedures under ultrasound-guided supraclavicular nerve block.Â.

排除标准

  • Coagulopathy Allergy to local anaesthetics Infection at site Pheriperal vascular disease.

结局指标

主要结局

The prediction of success or failure of supraclavicular block is early when compared to conventional method.

时间窗: Baseline,at 10 minutes,15,20,30 minutes

To calculate the perfusion index ratio.

时间窗: Baseline,at 10 minutes,15,20,30 minutes

次要结局

  • To predict the cut-off value for the perfusion index(10 minutes)

研究者

发起方
Velammal Medical College and Research Institute
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Ramadevi P

Velammal Medical College and Research institute

研究点 (1)

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