In-hospital and Post-discharge Training of Older Medical Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Hospitalized Older Medical Patients
- Sponsor
- Copenhagen University Hospital, Hvidovre
- Enrollment
- 158
- Locations
- 1
- Primary Endpoint
- Mobility using the de Morton Mobility Index (DEMMI)
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
The project aims to investigate the clinical value of simple strength training during hospitalization and after discharge as part of an enhanced recovery programme for acutely admitted older medical patients, in order to prevent mobility decline following acute hospitalization.
Note 11/23/16: As noted in the protocol (doi: 10.1186/s13063-016-1309-1) we have obtained funding and ethical approval (H-2-2012-115/09-12-2016) to extend the study to achieve sufficient power to look more deeply into our secondary outcomes. This will constitute a secondary part of the trial (started Nov. 2016). The primary trial report will include data for the pre-specified sample size for which the last patient was assessed Oct. 2016. Hence, the primary completion date for part 1 was April 2016 and the study completion date for part 1 was Oct 2016. The trial status is still "recruiting" although this applies to part 2 of the study.
Investigators
Mette Merete Pedersen
PhD student
Copenhagen University Hospital, Hvidovre
Eligibility Criteria
Inclusion Criteria
- •\>=65 years of age
- •admitted from own home
Exclusion Criteria
- •Terminal illness
- •In treatment for diagnosed cancer
- •Assigned to physical rehabilitation in community
- •Chronic Obstructive Pulmonary Disease (COPD) patients participating in organized rehabilitation
- •Living outside of the municipalities of Copenhagen and Broendby
- •Not able to talk and understand danish
- •Not able to cooperate on tests/exercises
- •Hospitalized \< 24 hours
- •A Cumulated Ambulation Score (CAS) of 0 in the sit-to-stand item
Outcomes
Primary Outcomes
Mobility using the de Morton Mobility Index (DEMMI)
Time Frame: Admittance (baseline), discharge, 4 weeks after discharge (primary analysis), and 26 weeks after discharge
The DEMMI is an advanced instrument for accurately measuring the mobility of older people across clinical settings (www.demmi.org.au). The primary analysis for the primary outcome is the change in the DEMMI score from baseline to the assessment 4 weeks after discharge (end of intervention). The primary analysis will follow the intention-to-treat principle (last observation carried forward) and be unadjusted in order to determine a systematic group-difference in the change from baseline to 4 weeks post discharge (end of training) for the primary outcome.
Secondary Outcomes
- Hand-grip strength of dominant hand(Admittance (baseline), discharge, 4 weeks post discharge and 26 weeks post discharge)
- 30-sec sit to stand test(Admittance (baseline), discharge, 4 weeks post discharge, 26 weeks post discharge)
- 24-hour mobility(Admittance to discharge, discharge to 1 week post discharge, 4 weeks post discharge to 5 weeks post discharge, 26 weeks post discharge to 27 weeks post discharge (4 x 1 week))
- Isometric knee-extension strength in dominant leg(At admittance (baseline), at discharge, 4 weeks after discharge and 26 weeks after discharge)
- Habitual gait speed(Admittance (baseline), discharge, 4 weeks post discharge, 26 weeks post discharge)