Memory Intervention with Nutrition for Dementia (re-MIND)

Not Applicable

Completed

• Conditions: Alzheimer's disease; Nervous System Diseases

• Registration Number: ISRCTN11892249
• Lead Sponsor: ow-Science Consultancy Limited

Brief Summary

2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36093704/ (added 06/01/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-06-20
• Study Completion: 2021-06-30
• Last Update Posted: 16 January 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 77

Inclusion Criteria

1. Diagnosis of mild to moderate Alzheimer's disease
2. Aged >65 years

Exclusion Criteria

1. Consumption of carotenoids and/or omega supplements within the last 3 months
2. Inability to swallow capsules
3. Depression (under active review and medication change)
4. Previously confirmed stroke disease and/or infarct on brain scan
5. Mini-Mental State Evaluation (MMSE) >24
6. Intact clock drawing test and semantic fluency test (i.e. naming more than 11 objects starting with the letter F in 1 minute)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
AD progression assessed using using mini mental state examination (MMSE) at baseline (visit 1), 12 months (visit 2) and 24 months (final visit). MMSE is a 30-point questionnaire that can be used to systematically and thoroughly assess mental status. It is an 11-question measure that tests five areas of cognitive function: orientation, registration, attention and calculation, recall, and language. Mild to moderate AD is defined as score of 10 to 25.