Compression Treatment of Superficial Vein Thrombosis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pain
- Sponsor
- Medical University of Vienna
- Enrollment
- 80
- Primary Endpoint
- pain assessed by VAS (cm)
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
Leg compression is considered the basic treatment for superficial vein thrombosis (SVT). However, its use is more or less based on subjective experience while scientific evidence for its efficacy is lacking. There is one uncontrolled trial reporting improvement of clinical symptoms when patients with SVT were treated with fixed compression bandages.
This study evaluates the efficacy of compression stockings (23-32 mmHg) in the treatment SVT of the legs. The investigators hypothesis is that compression treatment is superior to no compression in alleviating disease related clinical symptoms.
Investigators
Kornelia Boehler
MD
Medical University of Vienna
Eligibility Criteria
Inclusion Criteria
- •patients with superficial vein thrombosis of the leg,
- •thrombus extent of at least 5 cm confirmed by duplex sonography,
- •clinical signs of inflammation (pain, erythema)
Exclusion Criteria
- •superficial thrombus distance to the saphenofemoral or saphenopopliteal junction of less than 2cm,
- •concomitant deep vein thrombosis,
- •thrombophilia,
- •active malignoma,
- •immobility,
- •peripheral arterial occlusive disease,
- •superficial vein thrombosis after sclerotherapy
- •incision and clot expression
- •excessive leg configuration not covered by ready made compression stockings
Outcomes
Primary Outcomes
pain assessed by VAS (cm)
Time Frame: at baseline, week 1, week 2, week 3
change from baseline to week 3 at weekly intervals
Secondary Outcomes
- amount of analgetics (number of pills)(week 1, week 2, week 3)
- duplex-sonographic confirmation of deep vein thrombosis(at baseline and at week 3)
- skin erythema (cm2)(at baseline, week 1, week 2, week 3)
- quality of life (SF-36)(at baseline and at week 3)
- löwenberg test (mm Hg)(at baseline, week 1, week 2, week 3)
- duplex-sonographic change in thrombus length (cm)(at baseline, week 1, week 2, week 3)